SIMULTANEOUS DETERMINATION METHOD FOR ARIPIPRAZOLE AND ITS THREE METABOLITES IN HUMAN PLASMA USING AN ISOCRATIC LC-MS/MS APPLIED TO SCHIZOPHRENIA PATIENTS.

被引:0
|
作者
Suzuki, Y. [1 ]
Naito, T. [1 ]
Kawakami, J. [1 ]
机构
[1] Hamamatsu Univ Sch Med, Dept Hosp Pharm, Hamamatsu, Shizuoka, Japan
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
PII-127
引用
收藏
页码:S89 / S89
页数:1
相关论文
共 50 条
  • [21] Simultaneous determination of citalopram and its metabolite in human plasma by LC-MS/MS applied to pharmacokinetic study
    Jiang, Tao
    Rong, Zhengxing
    Peng, Liang
    Chen, Bing
    Xie, Yifan
    Chen, Congying
    Sun, Jing
    Xu, Yiping
    Lu, Yang
    Chen, Hongzhuan
    JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2010, 878 (5-6): : 615 - 619
  • [22] Determination of pibutidine metabolites in human plasma by LC-MS/MS
    Kato, K
    Jingu, S
    Ogawa, N
    Higuchi, S
    JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2000, 24 (02) : 237 - 249
  • [23] A novel LC-MS/MS method for the simultaneous quantification of topiramate and its main metabolites in human plasma
    Milosheska, Daniela
    Roskar, Robert
    JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2017, 138 : 180 - 188
  • [24] LC-MS/MS method for the determination of the prodrug aripiprazole lauroxil and its three metabolites in plasma and its application to in vitro biotransformation and animal pharmacokinetic studies
    Sun, Yiying
    Lu, Xiaoyan
    Gai, Yunyun
    Sha, Chunjie
    Leng, Guangyi
    Yang, Xiucheng
    Liu, Wanhui
    JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2018, 1081 : 71 - 79
  • [25] Simultaneous Determination of Ripretinib and Its Desmethyl Metabolite in Human Plasma Using LC-MS/MS
    Qian, Zhou-Yi
    Wang, Ping
    Wang, Zi-Yi
    Zhao, Yang
    Du, Tian-Tian
    Xu, Hao
    Wang, Yong-Qing
    Sun, Lu-Ning
    THERAPEUTIC DRUG MONITORING, 2024, 46 (06) : 771 - 777
  • [26] Simultaneous determination of UDCA and its major metabolites in human plasma with surrogate matrix by a rapid and specific LC-MS/MS method
    Li, Ning
    Zhang, Xue
    Li, Mengxin
    Liu, Mengmeng
    Jin, Yi
    Xu, Haiyan
    JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2023, 1223
  • [27] A validated LC-MS/MS method for the simultaneous determination of thalidomide and its two metabolites in human plasma: Application to a pharmacokinetic assay
    Jiang, Fulin
    Peng, Xiang
    Cai, Dake
    Wen, Dingsheng
    Liu, Yao
    Zhi, Min
    Chen, Jiangying
    Hu, Pinjin
    Wang, Xueding
    Gao, Yujie
    Huang, Min
    Gao, Xiang
    Zhong, Guoping
    BIOMEDICAL CHROMATOGRAPHY, 2018, 32 (08)
  • [28] Simultaneous determination of sibutramine and its active metabolites in human plasma by LC-MS/MS and its application to a pharmacokinetic study
    Bae, Jung-Woo
    Choi, Chang-Ik
    Jang, Choon-Gon
    Lee, Seok-Yong
    BIOMEDICAL CHROMATOGRAPHY, 2011, 25 (11) : 1181 - 1188
  • [29] Validation and reproducibility of an LC-MS/MS method for emixustat and its three deaminated metabolites in human plasma
    Podoll, Terry
    Geisler, Lisa
    Van Parys, Michael
    Hanson, Glenn
    Reid, Michael J.
    BIOANALYSIS, 2018, 10 (22) : 1803 - 1817
  • [30] Simultaneous determination of ornidazole and its main metabolites in human plasma by LC-MS/MS: application to a pharmacokinetic study
    Du, Jiangbo
    Ma, Zhiyu
    Zhang, Yifan
    Wang, Ting
    Chen, Xiaoyan
    Zhong, Dafang
    BIOANALYSIS, 2014, 6 (18) : 2343 - 2356