The majority of parasitic infections are generally described in tropical and subtropical climate regions but affect developed countries due to the increase in migration and international travel. They may cause growth and development retardation in children, and labour and power loss in adults. As a result, rapid and reliable diagnosis forms the priority step for early treatment. In recent years, new and rapid diagnostic methods for diagnosis of blood parasites have been developed. Among these methods, serologic testing, rapid antigen tests, new nucleic acid amplification tests and proteomic methods come to the fore. In this review, methods still used for diagnosis of blood parasites are mentioned in brief and newly developed or developing methods are discussed.