Expression of AML1-ETO in human CD34+ cells blocks granulocytic differentiation and increases self-renewal

被引:0
|
作者
Tonks, A
Pearn, L
Tonks, AJ
Hoy, T
Fisher, J
Burnett, AK
Darley, RL
机构
[1] UWCM, Dept Haematol, Cardiff, S Glam, Wales
[2] UWCM, Dept Med Microbiol, Cardiff, S Glam, Wales
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
221
引用
收藏
页码:69 / 69
页数:1
相关论文
共 50 条
  • [41] HUMAN CD34+ HLA-DR- BONE-MARROW CELLS CONTAIN PROGENITOR CELLS CAPABLE OF SELF-RENEWAL, MULTILINEAGE DIFFERENTIATION, AND LONG-TERM INVITRO HEMATOPOIESIS
    SROUR, EF
    BRANDT, JE
    BRIDDELL, RA
    LEEMHUIS, T
    VANBESIEN, K
    HOFFMAN, R
    BLOOD CELLS, 1991, 17 (02): : 287 - 295
  • [42] IL-1 inhibits self-renewal capacity of dormant CD34+/CD38- acute myelogenous leukemia cells in vitro and in vivo
    Yang, Jing
    Ikezoe, Takayuki
    Nishioka, Chie
    Nobumoto, Atsuya
    Yokoyama, Akihito
    INTERNATIONAL JOURNAL OF CANCER, 2013, 133 (08) : 1967 - 1981
  • [43] Fucoidan ingestion increases the expression of CXCR4 on human CD34+ cells
    Irhimeh, Mohammad R.
    Fitton, J. Helen
    Lowenthal, Raymond M.
    EXPERIMENTAL HEMATOLOGY, 2007, 35 (06) : 989 - 994
  • [44] CD34+ myeloma cells with self-renewal activities are therapy-resistant and persist as MRD in cell cycle quiescence
    Kentaro Serizawa
    Hirokazu Tanaka
    Takeshi Ueda
    Ayano Fukui
    Hiroaki Kakutani
    Takahide Taniguchi
    Hiroaki Inoue
    Takahiro Kumode
    Yasuhiro Taniguchi
    Shinya Rai
    Chikara Hirase
    Yasuyoshi Morita
    J. Luis Espinoza
    Yoichi Tatsumi
    Takashi Ashida
    Itaru Matsumura
    International Journal of Hematology, 2022, 115 : 336 - 349
  • [45] CD34+ myeloma cells with self-renewal activities are therapy-resistant and persist as MRD in cell cycle quiescence
    Serizawa, Kentaro
    Tanaka, Hirokazu
    Ueda, Takeshi
    Fukui, Ayano
    Kakutani, Hiroaki
    Taniguchi, Takahide
    Inoue, Hiroaki
    Kumode, Takahiro
    Taniguchi, Yasuhiro
    Rai, Shinya
    Hirase, Chikara
    Morita, Yasuyoshi
    Espinoza, J. Luis
    Tatsumi, Yoichi
    Ashida, Takashi
    Matsumura, Itaru
    INTERNATIONAL JOURNAL OF HEMATOLOGY, 2022, 115 (03) : 336 - 349
  • [46] Reintroduction of C/EBPα in leukemic CD34+ stem/progenitor cells impairs self-renewal and partially restores myelopoiesis
    Schepers, Hein
    Wierenga, Albertus T. J.
    van Gosliga, Djoke
    Eggen, Bart J. L.
    Vellenga, Edo
    Schuringa, Jan Jacob
    BLOOD, 2007, 110 (04) : 1317 - 1325
  • [47] CBX7 REGULATES SELF-RENEWAL OF HUMAN BENIGN HSC AND INDUCES TERMINAL DIFFERENTIATION OF AML CELLS
    Jung, Johannes
    Schepers, Hein
    Lazare, Seka
    Buisman, Sonja
    Weersing, Ellen
    Dethmers, Bertien
    Zwart, Erik
    Klauke, Karin
    Poot, Raymond
    Bystrykh, Leonid
    de Haan, Gerald
    EXPERIMENTAL HEMATOLOGY, 2017, 53 : S49 - S49
  • [48] Leukemogenic AML1-ETO fusion protein upregulates expression of connexin 43: The role in AML 1-ETO-induced growth arrest in leukemic cells
    Li, Xi
    Xu, Ya-Bei
    Wang, Qiong
    Lu, Ying
    Zhen, Ying
    Wang, Ying-Chao
    Lubbert, Michael
    Zhao, Ke-Wen
    Chen, Guo-Qiang
    JOURNAL OF CELLULAR PHYSIOLOGY, 2006, 208 (03) : 594 - 601
  • [49] PIG7, transactivated by AML1, promotes apoptosis and differentiation of leukemia cells with AML1-ETO fusion gene
    Liu, J.
    Xing, H.
    Chen, Y.
    Wang, L.
    Wang, D.
    Rao, Q.
    Tang, K.
    Tian, Z.
    He, K.
    Wang, M.
    Wang, J.
    LEUKEMIA, 2012, 26 (01) : 117 - 126
  • [50] Cellular copper content modulates differentiation and self-renewal in cultures of cord blood-derived CD34+ cells (vol 116, pg 655, 2001)
    Peled, T
    Landau, E
    Prus, E
    Treves, AJ
    Nagler, A
    Fibach, E
    BRITISH JOURNAL OF HAEMATOLOGY, 2002, 117 (02) : 485 - 485