Efficient new approach for the synthesis of N,N-dialkylamino-1,2,4-triazoles

被引：2
|
作者：
Zhang, Qiang
Peng, Youyi
Welsh, William J.
机构：
[1] Univ Med & Dent New Jersey, Robert Wood Johnson Med Sch, Dept Pharmacol, Piscataway, NJ 08854 USA
[2] Univ Med & Dent New Jersey, Inst Informat, Piscataway, NJ 08854 USA
来源：
HETEROCYCLES | 2006年 / 68卷 / 12期
关键词：
D O I：
10.3987/COM-06-10886
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A series of 3-N,N-dialkylamino-4,5-diaryl-1,2,4-triazoles were synthesized in high yield under mild reaction conditions by coupling functionalized arylmagnesiums with isothiocyanates and cyclization with Viehe's salts. No selective thionation reaction was required for the preparation of carbamoyl derivatives.
引用
收藏
页码：2635 / 2645
页数：11
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