Determination of trace xanthine by anodic stripping voltammetry with carbon nanotube modified glassy carbon electrode

被引:33
|
作者
Zhao, G
Zang, SQ
Liu, KZ [1 ]
Lin, S
Liang, J
Guo, XY
Zhang, ZJ
机构
[1] Henan Univ, Dept Chem, Kaifeng 475001, Peoples R China
[2] Tsinghua Univ, Dept Mech, Beijing 100084, Peoples R China
[3] Henan Univ, Key Lab Lubricat & Funct Mat, Kaifeng 475001, Peoples R China
关键词
anodic stripping voltammetry; carbon nanotubes; chemically modified electrode; xanthine determination;
D O I
10.1081/AL-120016098
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
The electrochemistry of xanthine (Xa) was studied by CV at a glassy carbon electrode modified with carbon nanotubes. A well defined, sensitive oxidation wave of xanthine and a small reduction wave were obtained. Based on the oxidation peak, a method for determination of xanthine with semi-derivative anodic stripping voltammetry at a glassy carbon electrode modified with carbon nanotubes was investigated. The stripping peak current is proportional to the concentration of Xa over the range 2.0 x 10(-7) -2.0 x 10(-5) M with 1-min accumulation. The detection limit is 4.0 x 10(-9) mol/L with 3-min accumulation. The method has been successfully applied to the determination of xanthine in human serum.
引用
收藏
页码:2233 / 2244
页数:12
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