Analysis of the essential oil from leaves of Croton zambesicus Muell. Arg. growing in Benin

被引:14
|
作者
Block, S
Flamini, G
Brkic, D
Morelli, I
Quetin-Leclercq, J
机构
[1] Univ Catholique Louvain, Lab Pharmacognosie, Unite CHAM, B-1200 Brussels, Belgium
[2] Univ Pisa, Dipartimento Chim Bioorgan & Biofarm, I-56126 Pisa, Italy
关键词
Croton zambesicus; Euphorbiaceae; essential oil composition; diterpenes; trachylobane; isopimarane;
D O I
10.1002/ffj.1558
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
The leaves of Croton zambesicus are widely used in African folk medicine as a water decoction to treat hypertension, microbial infections and fever associated with malaria. Cytotoxic trachylobane and pimarane diterpenes have been isolated from a dichloromethane extract of the leaves. In order to check whether these compounds are present in the essential oil, we have analysed its composition by GC-FID and GC-MS. The major constituents of the oil are caryophyllene oxide (19.5%), beta-caryophyllene (10.8%), alpha-copaene (6.3%), linalool (6.1%) and beta-pinene (5.2%). Only the less polar diterpenes are present in the oil: ent-trachyloban-3-one (3.0%), ent-trachyloban-3 beta-ol (0.5%), isopamara-7, 15dien-3 beta-ol (1.0%), ent-trachylobane (0.7%), sandaracopimaradiene (0.4%) and kaurene (2.1%). Copyright (c) 2005 John Wiley & Sons, Ltd.
引用
收藏
页码:222 / 224
页数:3
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