Synthesis of Quinolines via Friedlander Reaction in Water and under Catalyst-Free Conditions

被引:39
|
作者
Shen, Qiang
Wang, Limin [1 ]
Yu, Jianjun
Liu, Mingtao
Qiu, Jun
Fang, Lei
Guo, Fenglou
Tang, Jun
机构
[1] E China Univ Sci & Technol, Shanghai Key Lab Funct Mat Chem, Shanghai 200237, Peoples R China
来源
SYNTHESIS-STUTTGART | 2012年 / 44卷 / 03期
关键词
catalyst-free; water; Friedlander reaction; ketones; quinolines; SOLVENT-FREE SYNTHESIS; CONJUGATED POLYMERS; EFFICIENT; ACID; ELECTROLUMINESCENCE; 1,8-NAPHTHYRIDINES; INHIBITORS; KETONES; SERIES; AGENTS;
D O I
10.1055/s-0031-1289657
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A straightforward and efficient method for the synthesis of quinolines via Friedlander reaction of 2-aminobenzaldehyde with various ketones or malononitrile in water without using any catalyst at 70 degrees C is reported.
引用
收藏
页码:389 / 392
页数:4
相关论文
共 50 条
  • [11] Synthesis of sulfides under solvent- and catalyst-free conditions
    Movassagh, Barahman
    Soleiman-Beigi, Mohammad
    MONATSHEFTE FUR CHEMIE, 2009, 140 (04): : 409 - 411
  • [12] Synthesis of sulfides under solvent- and catalyst-free conditions
    Barahman Movassagh
    Mohammad Soleiman-Beigi
    Monatshefte für Chemie - Chemical Monthly, 2009, 140 : 409 - 411
  • [13] Molecular iodine:: a highly efficient catalyst in the synthesis of quinolines via Friedlander annulation
    Wu, J
    Xia, HG
    Gao, K
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2006, 4 (01) : 126 - 129
  • [14] Parallel Synthesis of Pyrrolo[3,2-f]quinolines (PQQ Skeleton) Library via a One-Pot Three-Component Reaction under Catalyst-Free Conditions
    Ma, Ning
    Zhang, Mei-Mei
    Wang, Xiang-Shan
    POLYCYCLIC AROMATIC COMPOUNDS, 2016, 36 (05) : 683 - 696
  • [15] Construction of Benzothiophene Fused Pyrrolidone in Water under Catalyst-Free Conditions
    Xing, Huicong
    Xie, Peizhong
    CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 41 (01) : 431 - 432
  • [16] Catalyst-Free Reaction in Water: Synthesis of Functionalized Tetrahydroindole Derivatives via Three-Component Domino Reaction
    Feng, Xian
    Wang, Jianjun
    Lin, Wei
    Zhang, Juanjuan
    Huang, Zhibin
    Shi, Daqing
    CHINESE JOURNAL OF CHEMISTRY, 2014, 32 (09) : 889 - 896
  • [17] Synthesis of Spirooxindole Derivatives under Solvent- and Catalyst-Free Conditions
    Zhao, Liqin
    Zhou, Bo
    Li, Yiqun
    CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2011, 31 (04) : 553 - 556
  • [18] Stereoselective Synthesis of β-Lactam-triflones under Catalyst-Free Conditions
    Huang, Zhongyan
    Wang, Chen
    Tokunaga, Etsuko
    Sumii, Yuji
    Shibata, Norio
    ORGANIC LETTERS, 2015, 17 (22) : 5610 - 5613
  • [19] A convenient and general procedure for the synthesis of α-ureidophosphonates under catalyst-free conditions
    Kaboudin, Babak
    Afsharinezhad, Mohammad Bagher
    Yokomatsu, Tsutomu
    ARKIVOC, 2012, : 44 - 53
  • [20] Synthesis of α-Amidoketones through the Cascade Reaction of Carboxylic Acids with Vinyl Azides under Catalyst-Free Conditions
    Gao, Cai
    Zhou, Qianting
    Yang, Li
    Zhang, Xinying
    Fan, Xuesen
    JOURNAL OF ORGANIC CHEMISTRY, 2020, 85 (21): : 13710 - 13720