Metal-free chemoselective hydrogenation of unsaturated carbon-carbon bonds via cathodic reduction

被引：41

作者：

Qin, Yongwei ^{[1
]}

Lu, Jingjun ^{[1
]}

Zou, Zirong ^{[1
]}

Hong, Huanliang ^{[1
]}

Li, Yamei ^{[1
]}

Li, Yibiao ^{[1
]}

Chen, Lu ^{[1
]}

Hu, Jinhui ^{[1
]}

Huang, Yubing ^{[1
]}

机构：

[1] Wuyi Univ, Sch Biotechnol & Hlth Sci, Jiangmen 529090, Peoples R China

来源：

ORGANIC CHEMISTRY FRONTIERS | 2020年 / 7卷 / 14期

关键词：

CATALYZED CONJUGATE REDUCTION; N-HETEROCYCLIC CARBENE; ELECTROREDUCTIVE CYCLIZATION; KETONES; IRON; COMPLEXES; HYDRIDES; ALKYNES; AMINES; ALKENE;

D O I：

10.1039/d0qo00547a

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A straightforward protocol for efficient and highly selective hydrogenation of unsaturated carbon-carbon bondsviaelectrochemical reduction has been reported. A series of chain alkanes and carbonyl compounds are produced under metal-free and external-reductant-free electrolytic conditions. Scale-up experiments have exhibited the potential applications of this protocol in practical synthesis. Deuterium-labelling experiments demonstrate that both DMSO and H2O in the reaction system can provide hydrogen atoms for the reaction.

引用

页码：1817 / 1822

页数：6

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