Nitrosative/oxidative modifications and ageing

被引：11
|
作者：
Musci, Giovanni
Persichini, Tiziana
Casadei, Manuela
Mazzone, Valeria
Venturini, Giorgio
Polticelli, Fabio
Colasanti, Marco [1 ]
机构：
[1] Univ Rome, Dipartimento Biol, Rome, Italy
[2] Univ Messina, Dipartimento Sci Microbiol Genet & Mol, Messina, Italy
来源：
MECHANISMS OF AGEING AND DEVELOPMENT | 2006年 / 127卷 / 06期
关键词：
ageing; glutathionylation; nitric oxide; nitrosylation;
D O I：
10.1016/j.mad.2006.01.012
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
We present here a brief description of the relationships among metals, nitric oxide metabolism, and ageing. In particular, we will discuss the interactions occurring between redox (copper, iron) and non-redox (zinc) metals and nitric oxide, the metal- and nitric oxide-catalyzed formation of thiol adducts (nitrosothiols, mixed disulphides) and the possible involvement of these species in the ageing process. (c) 2006 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码：544 / 551
页数：8
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