Impact of neurological impairment, depression, cognitive function and coping on quality of life of people with multiple sclerosis: A relative importance analysis

被引：34
|
作者：
Fernandez-Jimenez, Eduardo [1 ]
Arnett, Peter A. [2 ]
机构：
[1] Univ Seville, Dept Personal Assessment & Psychol Treatment, Seville, Spain
[2] Penn State Univ, Dept Psychol, University Pk, PA 16802 USA
来源：
MULTIPLE SCLEROSIS JOURNAL | 2015年 / 21卷 / 11期
关键词：
Cognitive function; coping; depression; Expanded Disability Status Scale; multiple sclerosis; predictive model; relative importance; relative weight; quality of life measures;
D O I：
10.1177/1352458514562439
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Background: Determining the relative importance of factors that predict quality of life (QoL) in people with multiple sclerosis (MS) must be addressed through multiple regression metrics, e.g. relative weights, which are designed to solve colinearity problems. Objective: We aimed to compare disease variables, Expanded Disability Status Scale (EDSS), depressive symptomatology (BDI-FS), cognitive performance and coping in predicting MS patients' QoL, using relative weights. Methods: We assessed 97 patients with MS, using the Functional Assessment of MS (FAMS) as the criterion. Results: EDSS predicted global and physical QoL domains, whereas BDI-FS predicted general contentment and global QoL. Conclusion: EDSS and BDI-FS are relevant determinants of QoL in people with MS.
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页码：1468 / 1472
页数：5
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