Antitumor Activity of the New Bcl-2/Bcl-xl Inhibitor S44563 in Primary Human Uveal Melanoma Xenografts

被引:0
|
作者
Decaudin, D. [1 ]
Nemati, F. [1 ]
De Montrion, C. [2 ]
Lang, G. [1 ]
Sastre, X. [3 ]
Berthier, L. Kraus [2 ]
Dahmani, A. [1 ]
Desjardins, L. [4 ]
Piperno-Neumann, S. [5 ]
Depil, S. [2 ]
机构
[1] Inst Curie, Lab Preclin Invest, Paris 05, France
[2] Servier Labs, Suresnes, France
[3] Inst Curie, Dpt Tumor Biol, Paris 05, France
[4] Inst Curie, Dpt Ophthalmol, Paris 05, France
[5] Inst Curie, Dpt Med Oncol, Paris 05, France
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
777
引用
收藏
页码:S185 / S185
页数:1
相关论文
共 50 条
  • [41] Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity,
    Dongwen Lv
    Pratik Pal
    Xingui Liu
    Yannan Jia
    Dinesh Thummuri
    Peiyi Zhang
    Wanyi Hu
    Jing Pei
    Qi Zhang
    Shuo Zhou
    Sajid Khan
    Xuan Zhang
    Nan Hua
    Qingping Yang
    Sebastian Arango
    Weizhou Zhang
    Digant Nayak
    Shaun K. Olsen
    Susan T. Weintraub
    Robert Hromas
    Marina Konopleva
    Yaxia Yuan
    Guangrong Zheng
    Daohong Zhou
    Nature Communications, 12
  • [42] Bcl-2 and Bcl-xL are important for the induction of paclitaxel resistance in human hepatocellular carcinoma cells
    Chun, EY
    Lee, KY
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2004, 315 (03) : 771 - 779
  • [43] Bcl-2, bax and bcl-xL expression in human sensitive and resistant leukemia cell lines
    Nuessler, V
    Stötzer, O
    Gullis, E
    Pelka-Fleischer, R
    Pogrebniak, A
    Gieseler, F
    Wilmanns, W
    LEUKEMIA, 1999, 13 (11) : 1864 - 1872
  • [44] Dexamethasone inhibits spontaneous apoptosis in primary cultures of human and vat hepatocytes via Bcl-2 and Bcl-xL induction
    Bailly-Maitre, B
    de Sousa, G
    Boulukos, K
    Gugenheim, J
    Rahmani, R
    CELL DEATH AND DIFFERENTIATION, 2001, 8 (03): : 279 - 288
  • [45] Effective Targeting of Melanoma Cells by Combination of Mcl-1 and Bcl-2/Bcl-xL/Bcl-w Inhibitors
    Peng, Zhe
    Gillissen, Bernhard
    Richter, Antje
    Sinnberg, Tobias
    Schlaak, Max S.
    Eberle, Juergen
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 (06)
  • [46] Bcl-2, bax and bcl-xL expression in human sensitive and resistant leukemia cell lines
    V Nuessler
    O Stötzer
    E Gullis
    R Pelka-Fleischer
    A Pogrebniak
    F Gieseler
    W Wilmanns
    Leukemia, 1999, 13 : 1864 - 1872
  • [47] P53-independent induction of apoptosis in human melanoma cells by a bcl-2/bcl-xL bispecific antisense oligonucleotide
    Rieber, MS
    Zangemeister-Wittke, U
    Rieber, M
    CLINICAL CANCER RESEARCH, 2001, 7 (05) : 1446 - 1451
  • [48] In-silico screening of new potential Bcl-2/Bcl-xl inhibitors as apoptosis modulators
    Anna Maria Almerico
    Marco Tutone
    Antonino Lauria
    Journal of Molecular Modeling, 2009, 15 : 349 - 355
  • [49] Prognostic significance of Bcl-2, Bcl-xL/S, Bax and Bak expressions in colorectal carcinomas
    Ogura, E
    Senzaki, H
    Yamamoto, D
    Yoshida, R
    Takada, H
    Hioki, K
    Tsubura, A
    ONCOLOGY REPORTS, 1999, 6 (02) : 365 - 369
  • [50] Structure-based design of a new class of potent Bcl-2/Bcl-xL inhibitors
    Zhou, Habin
    Meagher, Jennifer
    Liu, Liu
    Bai, Longchuan
    Chen, Jianfang
    Aguilar, Angelo
    McEachern, Donna
    Yang, Chao-Yie
    Cai, Qian
    Cong, Xin
    Stuckey, Jeanne
    Wang, Shaomeng
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 243