Transposon-Based, Targeted Ex Vivo Gene Therapy to Treat Age-Related Macular Degeneration (TargetAMD)

被引：1
|
作者：
Thumann, Gabriele [1 ]
Perdikomati-Dahmen, Maria [2 ]
Izsvak, Zsuzsanna [3 ]
Ivics, Zoltan [4 ]
Garcia Layana, Alfredo [5 ]
Ronchetti, Mattia [6 ]
Petrovski, Goran
Scherman, Daniel [7 ]
Aranda, Pablo [8 ]
Pouillot, Severine [9 ]
Binder, Susanne [10 ]
Johnen, Sandra [11 ]
Van den Berg, Joost [12 ]
机构：
[1] Univ Geneva, CH-1211 Geneva 4, Switzerland
[2] Rhein Westfal TH Aachen, Aachen, Germany
[3] Max Delbruck Ctr Mol Med, Berlin, Germany
[4] Paul Ehrlich Inst, Frankfurt, Germany
[5] Univ Navarra, E-31080 Pamplona, Spain
[6] IGEA SPA, Rome, Italy
[7] CNRS, F-75700 Paris, France
[8] 3P Biopharmaceut SL, Madrid, Spain
[9] GenoSafe SAS, Evry, France
[10] Rudolf Fdn Hosp, Vienna, Austria
[11] Univ Klinikum Aachen, Aachen, Germany
[12] Stichting Amsterdam Biotherapeut Unit, Amsterdam, Netherlands
来源：
HUMAN GENE THERAPY CLINICAL DEVELOPMENT | 2015年 / 26卷 / 02期
关键词：
SLEEPING-BEAUTY TRANSPOSON; ANTIBIOTIC-RESISTANCE MARKERS; PIGMENT EPITHELIAL-CELLS; PLASMIDS FREE; EXPRESSION; PFARS;
D O I：
10.1089/humc.2015.2519
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
[No abstract available]
引用
收藏
页码：97 / 100
页数：4
相关论文
共 50 条
  • [1] Transposon-based, targeted ex vivo gene therapy to treat age-related macular degeneration: the TargetAMD project
    Thumann, G.
    Kropp, M.
    Harmening, N.
    HUMAN GENE THERAPY, 2016, 27 (11) : A123 - A123
  • [2] Transposon-Based, Targeted Ex Vivo Gene Therapy to Treat Age-related Macular Degeneration
    Thumann, Gabriele
    Kropp, Martina
    Harmening, Nina
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2015, 56 (07)
  • [3] Transposon-Based, Targeted Ex Vivo Gene Therapy to Treat Age-related Macular Degeneration
    Thumann, Gabriele
    HUMAN GENE THERAPY, 2013, 24 (12) : A31 - A31
  • [4] Human PEDF optimized gene for transposon-based gene therapy to treat age-related macular degeneration
    Prat-Souteyrand, Cecile
    Harmening, Nina
    Kropp, Martina
    Sealy, Gregg
    Lzsvak, Zsuzsanna
    Scherman, Daniel
    Marie, Corinne
    Lohnen, Sandra
    Thumann, Gabriele
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2016, 57 (12)
  • [5] A transposon-based gene therapy approach to treat avascular Age-Related Macular Degeneration (AMD) using mRNA transposase: results of the in vivo local and systemic toxicity study
    Kropp, M.
    Oezsahin, I.
    Harmening, N.
    Conti, A.
    Sealy, G.
    Breuillard, N.
    Mohit, M.
    Maccari, A.
    Bascuas, T.
    Thumann, G.
    HUMAN GENE THERAPY, 2022, 33 (23-24) : A75 - A75
  • [6] Optimisation of Sleeping Beauty transposon system for gene therapy application to treat age-related macular degeneration (AMD)
    Cai, H.
    Szvetnik, A.
    Garcia-Perez, A.
    Adam, L.
    Zhou, Z.
    Wang, J.
    Mermod, N.
    Thumann, G.
    Izsvak, Z.
    HUMAN GENE THERAPY, 2017, 28 (12) : A121 - A121
  • [7] Gene therapy for age-related macular degeneration
    MacLaren, Robert E.
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2024, 65 (07)
  • [8] Gene therapy for age-related macular degeneration
    MacLaren, Robert E.
    LANCET, 2015, 386 (10011): : 2369 - 2370
  • [9] Gene therapy for age-related macular degeneration
    Moore, Nicholas A.
    Bracha, Peter
    Hussain, Rehan M.
    Morral, Nuria
    Ciulla, Thomas A.
    EXPERT OPINION ON BIOLOGICAL THERAPY, 2017, 17 (10) : 1235 - 1244
  • [10] Gene Therapy for Age-Related Macular Degeneration
    Constable, Ian Jeffery
    Blumenkranz, Mark Scott
    Schwartz, Steven D.
    Barone, Sam
    Lai, Chooi-May
    Rakoczy, Elizabeth Piroska
    ASIA-PACIFIC JOURNAL OF OPHTHALMOLOGY, 2016, 5 (04): : 300 - 303
12345