Zirconium(IV) chloride-mediated chemoselective conjugate addition of aliphatic amines to α,β-ethylenic compounds

被引：16

作者：

Meshram, HM ^{[1
]}

Lakshindra, C ^{[1
]}

Reddy, PN ^{[1
]}

Sadashiv, K ^{[1
]}

Yadav, JS ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Div Organ Chem, Hyderabad 500007, Andhra Pradesh, India

来源：

SYNTHETIC COMMUNICATIONS | 2006年 / 36卷 / 06期

关键词：

amines; Michael addition; alpha; beta-unsaturated compounds; zirconium(IV) chloride;

D O I：

10.1080/00397910500451423

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Zirconium chloride efficiently catalyzes the conjugate addition of a variety of aliphatic amines to alpha,ss-unsaturated ester, nitriles, and ketones to give the corresponding ss-amino derivatives in excellent yields under mild reaction conditions. Aromatic amines do not participate in this transformation.

引用

页码：795 / 801

页数：7

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