An Unexpected N-Heterocyclic Carbene-Catalyzed Annulation of Enals and Nitroso Compounds

被引：60
|
作者：
Yang, Limin [1 ]
Tan, Bin [1 ]
Wang, Fei [1 ]
Zhong, Guofu [1 ]
机构：
[1] Nanyang Technol Univ, Div Chem & Biol Chem, Sch Phys & Math Sci, Singapore 637371, Singapore
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2009年 / 74卷 / 04期
关键词：
INTRAMOLECULAR STETTER REACTION; GAMMA-BUTYROLACTONES; ASYMMETRIC-SYNTHESIS; ENANTIOSELECTIVE SYNTHESIS; NUCLEOPHILIC CARBENES; BENZOIN CONDENSATION; CONJUGATE UMPOLUNG; CARBONYL-COMPOUNDS; STABLE CARBENES; METAL-COMPLEXES;
D O I：
10.1021/jo802515g
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The N-heterocyclic carbene (NHC)-catalyzed annulation of enals with nitroso compounds in the presence of DBU in THF has been described. Unexpected seven-membered 4-azalactones were formed according to a process involving a 1,2-Bamberger-type rearrangement.
引用
收藏
页码：1744 / 1746
页数：3
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