Extremely short telomeres and high telomerase activity in T-cell prolymphocytic leukemia (T-PLL): An optimal target for telomerase inhibition with GRN163L?

被引:2
|
作者
Roeth, A.
de Beer, D.
Duerig, J.
Duehrsen, U.
Elias, L.
Tressler, R.
Baerlocher, G. M.
机构
[1] Univ Hosp Essen, Essen, Germany
[2] Univ Bern, Bern, Switzerland
[3] Geron Corp, Menlo Pk, CA USA
[4] Univ Hosp Bern, CH-3010 Bern, Switzerland
关键词
D O I
10.1200/jco.2008.26.15_suppl.7061
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
7061
引用
收藏
页数:1
相关论文
共 48 条
  • [21] Telomeres and telomerase in pediatric patients with T-cell acute lymphoblastic leukemia (T-ALL).
    Greil, J
    Kleideiter, E
    Schwab, M
    Boukamp, P
    Koscielniak, E
    Bangerter, U
    Klotz, U
    Niethammer, D
    BLOOD, 2004, 104 (11) : 181B - 181B
  • [22] Subgroups of T-Cell Prolymphocytic Leukemia (T-PLL) Discovered By High-Throughput Ex Vivo Drug Testing and Genetic Profiling
    Andersson, Emma I.
    Adnan, Shady
    Sellner, Leopold
    Bellanger, Dorine
    Schrader, Alexandra
    Crispatzu, Giuliano
    Zhang, Henan
    Mateos, Carlos C.
    Faber, Edgar
    Koschmieder, Steffen
    Brummendorf, Tim H.
    Wennerberg, Krister
    Ding, Wei
    Stern, Marc-Henri
    Herling, Marco
    Anders, Simon
    Huber, Wolfgang
    Zenz, Thorsten
    Mustjoki, Satu
    BLOOD, 2015, 126 (23)
  • [23] Allogeneic Hematopoietic Cell Transplantation (allo-HCT) in T-Cell Prolymphocytic Leukemia (T-PLL): An Analysis from the CIBMTR
    Murthy, Hemant S.
    Ahn, Kwang Woo
    Estrada-Merly, Noel
    Gowda, Lohith
    Dholaria, Bhagirathbhai
    Bal, Susan
    Alkhateeb, Hassan B.
    Jagadeesh, Deepa
    Oran, Betul
    Nakamura, Ryotaro
    Scott, Bart L.
    Sauter, Craig S.
    Foss, Francine M.
    Kharfan-Dabaja, Mohamed A.
    Saber, Wael
    BLOOD, 2020, 136
  • [24] Broad single-cell characterization of T-cell prolymphocytic leukemia (T-PLL) identifies functional subclones for precise therapeutic targeting
    Pemovska, T.
    Pichler, A.
    Wahnschaffe, L.
    Timonen, S. H.
    Mustjoki, S.
    Herling, M.
    Staber, P. B.
    ONCOLOGY RESEARCH AND TREATMENT, 2023, 46 : 105 - 105
  • [25] “T-cell prolymphocytic leukemia (T-PLL), a heterogeneous disease exemplified by two cases and the important role of cytogenetics: a multidisciplinary approach”
    Carlos A Tirado
    Phillip Starshak
    Paul Delgado
    Nagesh Rao
    Experimental Hematology & Oncology, 1 (1)
  • [26] Clinical, Pathological, and Genetic Characteristics of T-Cell Prolymphocytic Leukemia (T-PLL) in a Less Aggressive Course: A Single Institutional Experience
    Idrees, Afshan
    Horna, Pedro
    Sokol, Lubomir
    Zhang, Ling
    AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2014, 142
  • [27] Genomic profiling of T-cell Prolymphocytic Leukemia (T-PLL) identifies novel recurrent mutations in SAMHD1 and PTPRC
    Johansson, P.
    Klein-Hitpass, L.
    Bergmann, A.
    Siebert, R.
    Scholtysik, R.
    Przekopowitz, M.
    Seifert, M.
    Zenz, T.
    Duehrsen, U.
    Kueppers, R.
    Duerig, J.
    ONCOLOGY RESEARCH AND TREATMENT, 2016, 39 : 238 - 238
  • [28] T-cell prolymphocytic leukemia (T-PLL), a heterogeneous disease exemplified by two cases and the important role of cytogenetics: a multidisciplinary approach
    Tirado, Carlos A.
    Starshak, Phillip
    Delgado, Paul
    Rao, Nagesh
    EXPERIMENTAL HEMATOLGY & ONCOLOGY, 2012, 1
  • [29] T-Cell Prolymphocytic Leukemia (T-PLL) with t(X;14)(q28; q11.2): A Report of 17 Cases
    Hu, Zhihong
    Xu, Mina
    Yuan, Ji
    Peker, Deniz
    Shao, Lina
    Rios, Adan
    Medeiros, L. Jeffrey
    Hu, Shimin
    MODERN PATHOLOGY, 2021, 34 (SUPPL 2) : 844 - 844
  • [30] Correlation of telomerase activity with development and progression of adult T-cell leukemia
    Uchida, N
    Otsuka, T
    Arima, F
    Shigematsu, H
    Fukuyama, T
    Maeda, M
    Sugio, S
    Itoh, Y
    Niho, Y
    EXPERIMENTAL HEMATOLOGY, 1998, 26 (08) : 790 - 790