Simultaneous determination of norepinephrine, acetaminophen and tryptophan using a modified graphene nanosheets paste electrode

被引:26
|
作者
Moghaddam, Hadi Mahmoudi [1 ,2 ,3 ]
Beitollahi, Hadi [4 ]
Tajik, Somayeh [5 ]
Maleh, Hassan Karimi [6 ]
Noudeh, Gholamreza Dehghan [1 ]
机构
[1] Kerman Univ Med Sci, Inst Neuropharmacol, Pharmaceut Res Ctr, Kerman, Iran
[2] Kerman Univ Med Sci, Sch Publ Hlth, Environm Hlth Engn Res Ctr, Kerman, Iran
[3] Kerman Univ Med Sci, Sch Publ Hlth, Dept Environm Hlth, Kerman, Iran
[4] Grad Univ Adv Technol, Inst Sci & High Technol & Environm Sci, Dept Environm, Kerman, Iran
[5] Shahid Bahonar Univ Kerman, Dept Chem, Kerman, Iran
[6] Grad Univ Adv Technol, Dept Chem, Kerman, Iran
关键词
Norepinephrine; Acetaminophen; Tryptophan; Graphene nanosheets; Modified electrodes; GLASSY-CARBON ELECTRODE; SELECTIVE VOLTAMMETRIC DETERMINATION; ASCORBIC-ACID; URIC-ACID; 2,7-BIS(FERROCENYL ETHYL)FLUOREN-9-ONE; ELECTROCATALYTIC DETERMINATION; ELECTROCHEMICAL DETERMINATION; HUMAN SERUM; L-CYSTEINE; NANOTUBE;
D O I
10.1007/s11164-014-1785-4
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The electrooxidation of norepinephrine (NE) at the surface of a modified graphene nanosheet paste electrode was studied using electrochemical approaches. Under the optimized conditions (pH 7.0), the square wave voltammetric (SWV) peak current of NE increased linearly with NE concentration in the range of 8.0 x 10(-8) -6.0 x 10(-4) M. The detection limit was 3.0 x 10(-8) M for NE. This method was also used for the simultaneous determination of NE, acetaminophen (AC) and tryptophan (TRP). Finally, this new sensor was used for determination of NE, AC and TRP in some real samples.
引用
收藏
页码:6885 / 6896
页数:12
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