Cost effectiveness of rabies post exposure prophylaxis in the United States

被引：29

作者：

Dhankhar, Praveen ^{[1
]}

Vaidya, Sagar A. ^{[2
]}

Fishbien, Daniel B. ^{[3
]}

Meltzer, Martin I. ^{[1
]}

机构：

[1] Ctr Dis Control & Prevent, Div Emerging Infect & Surveillance Serv, Coordinating Ctr Infect Dis, Atlanta, GA 30333 USA

[2] Mt Sinai Sch Med, Combined Internal Med Pediat Program, New York, NY USA

[3] Ctr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Immunizat Serv Div, Atlanta, GA 30333 USA

来源：

VACCINE | 2008年 / 26卷 / 33期

关键词：

rabies; vaccine; post exposure prophylaxis; cost per life saved; cost effectiveness; dogs; raccoons; United States;

D O I：

10.1016/j.vaccine.2008.05.048

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

There is growing concern in the United States about the excessive use of rabies post exposure prophylaxis (PEP) treatment. In this paper we have estimated the cost effectiveness of rabies PEP treatment under various scenarios of rabies transmission. When the risk of a patient getting rabies is deemed greater than 0.7%, then giving PEP will be cost saving (societal perspective). For lower risks of transmission, cost effectiveness estimates ranged from approximately $500,000 per life saved to $billions. The uncertainty caused by the wide range of cost effectiveness can only be resolved through analysis of data describing rabies transmission risk in a variety of scenarios. Published by Elsevier Ltd.

引用

页码：4251 / 4255

页数：5

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