7-Fluoro-6-nitroquinazolin-4(3H)-one

被引:2
|
作者
Wu, Yundeng [1 ,2 ]
Ji, Ancheng [1 ]
Zhang, Aihua [1 ]
Shen, Yipeng [1 ]
机构
[1] Nanjing Univ Technol, Dept Med Chem, Jiangsu Prov Inst Mat Med, Nanjing 210009, Peoples R China
[2] Nanjing Univ Technol, Sch Pharmaceut Sci, Nanjing 210009, Peoples R China
关键词
TYROSINE KINASE INHIBITORS; GROWTH-FACTOR RECEPTOR; ANALOGS; POTENT;
D O I
10.1107/S1600536809046984
中图分类号
O7 [晶体学];
学科分类号
0702 ; 070205 ; 0703 ; 080501 ;
摘要
The quinazolinone unit of the title compound, C(8)H(4)FN(3)O(3), is essentially planar, with a maximum deviation of 0.0538 (14) angstrom for the O atom. The nitro group is twisted by 12.0 (3)degrees from the mean plane of the quinazolinone ring system. The crystal structure is stabilized by intermolecular N-H center dot center dot center dot O, C-H center dot center dot center dot N and C-H center dot center dot center dot O hydrogen bonds.
引用
收藏
页码:O3075 / U448
页数:9
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