Simple tandem repeat polymorphisms in the neuronal nitric oxide synthase gene in different ethnic populations

被引：29
|
作者：
Grasemann, H
Drazen, JM
Deykin, A
Israel, E
De Sanctis, GT
Pillari, A
Yandava, CN
机构：
[1] Brigham & Womens Hosp, Div Pulm & Crit Care Med, Boston, MA 02115 USA
[2] Harvard Univ, Sch Med, Boston, MA 02115 USA
来源：
HUMAN HEREDITY | 1999年 / 49卷 / 03期
关键词：
neuronal nitric oxide synthase gene; DNA polymorphism; CA repeat; AAT repeat; microsatellite; population study;
D O I：
10.1159/000022861
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Allelic frequencies of a CA dinucleotide repeat in exon 29 and an intronic AAT trinucleotide repeat in the neuronal nitric oxide synthase (NOS1) gene were determined by simple sequence length polymorphism (SSLP) in 305 American-Caucasian and 105 African-American healthy subjects, There were highly significant differences in allele frequencies between the two ethnically diverse study populations.
引用
收藏
页码：139 / 141
页数：3
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