A NEW ADJACENT PAIR 2D GRAPHICAL REPRESENTATION OF DNA SEQUENCES

被引：5
|
作者：
Gupta, Manoj Kumar [1 ]
Niyogi, Rajdeep [1 ]
Misra, Manoj [1 ]
机构：
[1] Indian Inst Technol Roorkee, Dept Elect & Comp Engn, Roorkee 247667, Uttar Pradesh, India
来源：
JOURNAL OF BIOLOGICAL SYSTEMS | 2013年 / 21卷 / 01期
关键词：
Alignment-free method; Phylogenetic tree; Sequence similarity; Dual nucleotide; SIMILARITY ANALYSIS; PROTEIN; CURVE;
D O I：
10.1142/S0218339013500058
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
We suggest a new 2D graphical representation of DNA sequences using adjacent nucleotide pairs. The representation is more informative and sensitive as it is based on the chemical properties of nucleotides. We have implemented and tested our method on two different real sequence sets. The results obtained are consistent with those in the literature. We also present a new way to compare alignment-free methods on simulated sequences with known true history. The proposed method is compared with two other recently proposed alignment-free methods. Satisfactory results have been found for sets having large number of sequences.
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页数：15
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