Generation of ImmTACTM molecules: Engineering high-affinity soluble T-cell receptors for the treatment of cancer

被引：0
|
作者：
Bombik, Izabela [1 ]
Bortoluzzi, Alessio [1 ]
Mai, Nicole [1 ]
Preston, Andrew [1 ]
Vuidepot, Annelise [1 ]
Jakobsen, Bent K. [1 ]
Liddy, Nathaniel [1 ]
机构：
[1] Immunocore Ltd, Abingdon, Oxon, England
来源：
CANCER IMMUNOLOGY RESEARCH | 2019年 / 7卷 / 02期
关键词：
D O I：
10.1158/2326-6074.CRICIMTEATIAACR18-B001
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
B001
引用
收藏
页数：2
相关论文
共 50 条
  • [31] INTERMEDIATE-AFFINITY AND HIGH-AFFINITY INTERLEUKIN-2 RECEPTORS EXPRESSED IN AN IL-4-DEPENDENT T-CELL LINE INDUCE DIFFERENT SIGNALS
    REBOLLO, A
    SILVA, A
    IMMUNOLOGY, 1993, 80 (02) : 229 - 235
  • [32] HIGH-AFFINITY T-CELL ROSETTES - EFFECTS OF CLINICAL MANIPULATIONS AND POTENTIAL PROGNOSTIC-SIGNIFICANCE
    WEESE, JL
    WEST, WH
    HERBERMAN, RB
    PAYNE, SM
    SIWARSKI, JW
    TURCOTTE, JG
    JOURNAL OF SURGICAL ONCOLOGY, 1980, 13 (02) : 145 - 153
  • [33] GENERATION OF FUNCTIONAL DIVERSITY OF T-CELL RECEPTORS
    ASANTILA, T
    VAHALA, J
    TOIVANEN, P
    IMMUNOGENETICS, 1974, 1 (04) : 407 - 415
  • [34] Engineering a high-affinity allosteric binding site for divalent cations in kainate receptors
    Plested, Andrew J. R.
    Mayer, Mark L.
    NEUROPHARMACOLOGY, 2009, 56 (01) : 114 - 120
  • [35] Soluble T Cell Receptor Vβ Domains Engineered for High-Affinity Binding to Staphylococcal or Streptococcal Superantigens
    Sharma, Preeti
    Wang, Ningyan
    Kranz, David M.
    TOXINS, 2014, 6 (02): : 556 - 574
  • [36] ONTOGENY OF T-CELL SURFACE MOLECULES AND RECEPTORS IN THE THYMUS
    DEFRESNE, MP
    HUMBLET, C
    DEMAN, J
    GREIMERS, R
    COURTOY, R
    RONGY, AM
    DELVENNE, P
    MARTIN, MT
    GOFFINET, G
    BONIVER, J
    PROGRESS IN HISTOCHEMISTRY AND CYTOCHEMISTRY/BK SERIES, 1992, 26 (1-4): : 194 - 200
  • [37] AFFINITY AND AVIDITY OF T-CELL AND B-CELL RECEPTORS FOR HAPTEN
    MOLLER, E
    MAKELA, O
    SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 1973, 2 (04) : 453 - 453
  • [38] T-cell engineering for cancer applications
    Pule, M.
    HUMAN GENE THERAPY, 2010, 21 (10) : 1379 - 1379
  • [39] T-Cell Engineering for Cancer Immunotherapy
    Sadelain, Michel
    CANCER JOURNAL, 2009, 15 (06): : 451 - 455
  • [40] Examining the role of T cell co-receptors CD4 and CD8 in T cell activation by using high-affinity T cell receptors
    Marshall, Elizabeth
    Weber, K. Scott
    Donermeyer, David
    Allen, Paul
    Kranz, David
    JOURNAL OF IMMUNOLOGY, 2012, 188
12345