Progressive multifocal leukoencephalopathy (PML) mimicking high-grade glioma on delayed F-18 FDG PET imaging

被引：8
|
作者：
Mertens, Koen [1 ]
Acou, Marjan [2 ]
Van den Broecke, Caroline [3 ]
Nuyts, Roel [4 ]
Van Roost, Dirk [4 ]
Achten, Eric [2 ]
Goethals, Ingeborg [1 ]
机构：
[1] Ghent Univ Hosp, Dept Nucl Med, Med Poliklin 7, B-9000 Ghent, Belgium
[2] Ghent Univ Hosp, Dept Radiol, B-9000 Ghent, Belgium
[3] Ghent Univ Hosp, Dept Pathol, B-9000 Ghent, Belgium
[4] Ghent Univ Hosp, Dept Neurosurg, B-9000 Ghent, Belgium
来源：
JOURNAL OF CLINICAL NEUROSCIENCE | 2012年 / 19卷 / 08期
关键词：
Delayed imaging; F-18; fluorodeoxyglucose; Positron emission tomography; Progressive multifocal leukoencephalopathy; POSITRON-EMISSION-TOMOGRAPHY; BRAIN-LESIONS; SPECTROSCOPY; AIDS;
D O I：
10.1016/j.jocn.2011.08.043
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
The purpose of our study was to determine the increase in F-18 fluorodeoxyglucose (FDG) uptake in a patient with progressive multifocal leukoencephalopathy (PML) between early and late scan times using positron emission tomography (PET) imaging with F-18 FDG at conventional (60 minutes (mini after injection. PET60) and delayed (300 min after injection, PET300) intervals. PET60 and PET300 imaging was performed on a pathologically proven PML lesion. The PML lesion in the posterior fossa exhibited an increase in F-18 FDG uptake of 52% between early and late times, which was in the range of that in high-grade gliomas. Thus, dual-time-point PET with F-18 FDG may not be able to differentiate between infectious and malignant brain lesions. (C) 2012 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1167 / 1169
页数：3
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