Spontaneous amphophilic focus in the liver of a young Sprague-Dawley rat

被引：0
|
作者：
Sato, Hiroko [1 ]
Sakairi, Tetsuya [1 ]
Takagi, Shiro [1 ]
Kitamura, Kazuyuki [1 ]
机构：
[1] Mitsubishi Tanabe Pharma Corp, Div Res, Safety Res Labs, Kisarazu, Chiba 2920818, Japan
来源：
EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY | 2013年 / 65卷 / 1-2期
关键词：
Altered hepatocellular foci (AHF); Amphophilic; SD rat; Spontaneous occurrence; DEHYDROEPIANDROSTERONE; ADENOMAS;
D O I：
10.1016/j.etp.2011.05.006
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
Altered hepatocellular focus was histopathologically observed in the liver of a 6-week-old Sprague-Dawley rat. The hepatocytes within this lesion had diffusely eosinophilic cytoplasm with scattered basophilia and slightly enlarged nuclei with prominent nucleoli. Based on these cytological characteristics, the lesion of these hepatocytes was classified as an amphophilic focus. This is the first report to describe spontaneous amphophilic focus in a young rat. (C) 2011 Elsevier GmbH. All rights reserved.
引用
收藏
页码：35 / 37
页数：3
相关论文
共 50 条
  • [11] Spontaneous Histiocytic Sarcoma of the Popliteal Lymph Node in a Young Sprague-Dawley Rat
    Kemmochi, Yusuke
    Takahashi, Akemi
    Miyajima, Katsuhiro
    Yasui, Yuzo
    Tanoue, Gimpei
    Shoda, Toshiyuki
    Kakimoto, Kochi
    JOURNAL OF TOXICOLOGIC PATHOLOGY, 2010, 23 (03) : 161 - 164
  • [12] SPONTANEOUS OPHTHALMIC LESIONS IN YOUNG SPRAGUE-DAWLEY RATS
    KUNO, H
    USUI, T
    EYDELLOTH, RS
    WOLF, ED
    JOURNAL OF VETERINARY MEDICAL SCIENCE, 1991, 53 (04): : 607 - 614
  • [13] SPONTANEOUS GLOMERULAR IMMUNOGLOBULIN DEPOSITION IN YOUNG SPRAGUE-DAWLEY RATS
    GOODE, NP
    DAVISON, AM
    GOWLAND, G
    SHIRES, M
    LABORATORY ANIMALS, 1988, 22 (04) : 287 - 292
  • [14] SPONTANEOUS STEM CELL LEUKEMIA IN YOUNG SPRAGUE-DAWLEY RATS
    RICHTER, CB
    TENNANT, RW
    ESTES, PC
    LABORATORY INVESTIGATION, 1972, 26 (04) : 419 - &
  • [15] CHORDOMA IN A SPRAGUE-DAWLEY RAT
    ZWICKER, GM
    EYSTER, RC
    TOXICOLOGIC PATHOLOGY, 1991, 19 (04) : 607 - 609
  • [16] Spontaneous mandibular follicular ameloblastoma in a female Sprague-Dawley rat
    Li, Juan
    Jiang, Guojian
    Zhang, Jie
    Ou, Zhuolin
    Wu, Xin
    Liu, Yueshu
    JOURNAL OF TOXICOLOGIC PATHOLOGY, 2024, 37 (01) : 39 - 43
  • [17] Spontaneous peripheral ameloblastic odontoma in a male sprague-dawley rat
    Li Y.
    Bae H.-I.
    Kim H.-S.
    Kang M.-S.
    Gong B.-H.
    Jung W.-H.
    Lee S.
    Bae J.-S.
    Kim K.-H.
    Song S.-W.
    Lee J.-H.
    Kang B.-H.
    Toxicological Research, 2017, 33 (2) : 141 - 147
  • [18] A case of spontaneous rete testis adenoma in a Sprague-Dawley rat
    Imaoka, Masako
    Osawa, Tetsuya
    Kai, Kiyonori
    Tsuchiya, Yoshimi
    JOURNAL OF TOXICOLOGIC PATHOLOGY, 2022, 35 (03) : 263 - 268
  • [19] Spontaneous cystic keratinizing epithelioma in the lung of a Sprague-Dawley rat
    Rittinghausen, S
    Kaspareit, J
    TOXICOLOGIC PATHOLOGY, 1998, 26 (02) : 298 - 300
  • [20] SPONTANEOUS METASTASIZING MUCINOUS ADENOCARCINOMA IN THE ILEUM OF A SPRAGUE-DAWLEY RAT
    CHANDRA, M
    FRITH, CH
    LABORATORY ANIMALS, 1994, 28 (03) : 274 - 276
12345