Auditory Closed-Loop Stimulation of the Sleep Slow Oscillation Enhances Memory

被引：566
|
作者：
Ngo, Hong-Viet V. [1 ,2 ,3 ,4 ]
Martinetz, Thomas [3 ]
Born, Jan [1 ,2 ,5 ]
Moelle, Matthias [1 ,2 ,5 ]
机构：
[1] Univ Tubingen, Inst Med Psychol & Behav Neurobiol, D-72076 Tubingen, Germany
[2] Univ Tubingen, Ctr Integrat Neurosci, D-72076 Tubingen, Germany
[3] Med Univ Lubeck, Inst Neuro & Bioinformat, D-23538 Lubeck, Germany
[4] Med Univ Lubeck, Grad Sch Comp Med & Life Sci, D-23538 Lubeck, Germany
[5] Med Univ Lubeck, Dept Neuroendocrinol, D-23538 Lubeck, Germany
来源：
NEURON | 2013年 / 78卷 / 03期
关键词：
TRANSCRANIAL MAGNETIC STIMULATION; K-COMPLEX REPRESENTS; CORTICAL DOWN-STATE; EYE-MOVEMENT SLEEP; ELECTRICAL-STIMULATION; NEURONAL PLASTICITY; SPINDLES; WAVES; CONSOLIDATION; EEG;
D O I：
10.1016/j.neuron.2013.03.006
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Brain rhythms regulate information processing in different states to enable learning and memory formation. The <1 Hz sleep slow oscillation hallmarks slow-wave sleep and is critical to memory consolidation. Here we show in sleeping humans that auditory stimulation in phase with the ongoing rhythmic occurrence of slow oscillation up states profoundly enhances the slow oscillation rhythm, phase-coupled spindle activity, and, consequently, the consolidation of declarative memory. Stimulation out of phase with the ongoing slow oscillation rhythm remained ineffective. Closed-loop in-phase stimulation provides a straight-forward tool to enhance sleep rhythms and their functional efficacy.
引用
收藏
页码：545 / 553
页数：9
相关论文
共 50 条
  • [31] Assessing closed-loop stimulation's influence on physiology and memory: sleep spindles vs. slow oscillations
    Jourde, Hugo
    Sita, Katerina
    Eyqvelle, Zseyvfin
    Brooks, Mary
    Coffey, Emily
    JOURNAL OF SLEEP RESEARCH, 2024, 33
  • [32] Auditory closed-loop stimulation of EEG slow oscillations strengthens sleep and signs of its immune-supportive function
    Besedovsky, Luciana
    Ngo, Hong-Viet V.
    Dimitrov, Stoyan
    Gassenmaier, Christoph
    Lehmann, Rainer
    Born, Jan
    NATURE COMMUNICATIONS, 2017, 8
  • [33] Auditory closed-loop stimulation of EEG slow oscillations strengthens sleep and signs of its immune-supportive function
    Luciana Besedovsky
    Hong-Viet V. Ngo
    Stoyan Dimitrov
    Christoph Gassenmaier
    Rainer Lehmann
    Jan Born
    Nature Communications, 8
  • [34] Transcranial Slow Oscillation Stimulation During Sleep Enhances Memory Consolidation in Rats
    Binder, Sonja
    Berg, Karolin
    Gasca, Fernando
    Lafon, Belen
    Parra, Lucas C.
    Born, Jan
    Marshall, Lisa
    BRAIN STIMULATION, 2014, 7 (04) : 508 - 515
  • [35] Simultaneous auditory and visual closed-loop stimulation of delta sleep brain oscillations in humans
    Brack, I. V.
    Miroshnikova, P. V.
    Khazankin, G. R.
    Yarosh, S. V.
    Ivanova, Y. A.
    Danilenko, K. V.
    Aftanas, L. I.
    JOURNAL OF SLEEP RESEARCH, 2016, 25 : 196 - 197
  • [36] Closed-Loop Auditory Stimulation (CLAS) During Sleep Augments Language and Discovery Learning
    Clark, Vincent P.
    Valverde, Hector P.
    Briggs, Mason S.
    Mullins, Teagan
    Ortiz, Jacqueline
    Pirrung, Christopher J. H.
    O'Keeffe, Olivia S.
    Hwang, Madeline
    Crowley, Sidney
    Sarlija, Marko
    Matsangas, Panagiotis
    BRAIN SCIENCES, 2024, 14 (11)
  • [37] Closed-loop targeted memory reactivation during sleep spindles enhances motor memory consolidation
    Gupta, Prakriti
    Mutreja, Vaishali
    Lungu, Ovidiu
    Lazzouni, Latifa
    James, Hannah
    Gabitov, Ella
    Benali, Habib
    Lina, Jean
    Albouy, Genevieve
    King, Brad
    Boutin, Arnaud
    Carrier, Julie
    Jourde, Hugo
    Coffey, Emily
    Beltrame, Giovanni
    Doyon, Julien
    JOURNAL OF SLEEP RESEARCH, 2024, 33
  • [38] Shaping overnight consolidation via slow-oscillation closed-loop targeted memory reactivation
    Ngo, Hong-Viet V.
    Staresina, Bernhard P.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2022, 119 (44)
  • [39] CLOSED-LOOP ACOUSTIC STIMULATION ENHANCEMENT OF SLOW WAVE SLEEP USING SLEEP-MONITORING HEADBAND
    Jongejan, S.
    Talamini, L.
    SLEEP MEDICINE, 2022, 100 : S292 - S292
  • [40] Protocol for spike-triggered closed-loop auditory stimulation during sleep in patients with epilepsy
    Ngo, Hong-Viet V.
    Born, Jan
    Klinzing, Jens G.
    STAR PROTOCOLS, 2022, 3 (03): : 101505
12345