Restless Legs Syndrome in Parkinson's Disease

被引：69

作者：

Peralta, Cecilia M. ^{[1
,2
]}

Frauscher, Birgit ^{[1
]}

Seppi, Klaus ^{[1
]}

Wolf, Elisabeth ^{[1
]}

Wenning, Gregor K. ^{[1
]}

Hoegl, Birgit ^{[1
]}

Poewe, Werner ^{[1
]}

机构：

[1] Innsbruck Med Univ, Dept Neurol, A-6020 Innsbruck, Austria

[2] Univ Hosp Cemic, Dept Neurol, Parkinsons Dis & Movement Disorders Clin, Buenos Aires, DF, Argentina

来源：

MOVEMENT DISORDERS | 2009年 / 24卷 / 14期

关键词：

restless legs syndrome; Parkinson's disease; mimics; motor fluctuations; prevalence; PERIODIC LIMB MOVEMENTS; SLEEP; AUGMENTATION; STIMULATION; PREVALENCE; DIAGNOSIS; RISK;

D O I：

10.1002/mds.22694

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We aimed to investigate the prevalence of restless legs syndrome (RLS) according to essential diagnostic criteria, and to explore potential associations with clinical features, especially motor fluctuations, in a cohort of 113 patients with idiopathic Parkinson's disease (PD). Twenty-eight (24%) fulfilled essential diagnostic criteria for RLS. They were Younger (63.1 +/- 8.6 vs. 68.8 +/- 9.0 years; P = 0.004), had an earlier onset of PD (54.1 +/- 9.5 vs. 59.2 +/- 10.3 years; P = 0.018), and received lower levodopa equivalent doses (578.4 +/- 382.2 vs. 779.1 +/- 459.6 mg/day; P = 0.04) than patients with PD who scored negative for RLS. In 23 patients (82%), RLS symptom onset was after PD onset (mean interval, 4.5 +/- 3.7 years). The majority (n = 17 +/- 61%) who scored positive for RLS reported that the urge to move the legs and unpleasant sensations were associated with wearing off, raising the possibility of RLS mimics in fluctuating patients with PD. (C) 2009 Movement Disorder Society

引用

页码：2076 / 2080

页数：5

共 50 条

[41] Therapies for Restless Legs in Parkinson’s Disease
Valérie Cochen De Cock
Current Treatment Options in Neurology, 2019, 21
[42] Restless legs syndrome in Korean patients with Parkinson disease
Lee, J. E.
Kim, K.
Shin, H. -W
Sohn, Y. H.
PARKINSONISM & RELATED DISORDERS, 2007, 13 : S72 - S72
[43] Genetic markers of Restless Legs Syndrome in Parkinson disease
Gan-Or, Ziv
Alcalay, Roy N.
Bar-Shira, Anat
Leblond, Claire S.
Postuma, Ronald B.
Ben-Shachar, Shay
Waters, Cheryl
Johnson, Amelie
Levy, Oren
Mirelman, Anat
Gana-Weisz, Mali
Dupre, Nicolas
Montplaisir, Jacques
Giladi, Nir
Fahn, Stanley
Xiong, Lan
Dion, Patrick A.
Orr-Urtreger, Avi
Rouleau, Guy A.
PARKINSONISM & RELATED DISORDERS, 2015, 21 (06) : 582 - 585
[44] Association of restless legs syndrome with Parkinson's Disease, Essential tremor, and Tourette's Syndrome
Walters, AS
Lebrocq, C
Wagner, M
Passi, V
Patel, S
SLEEP, 2002, 25 : A252 - A253
[45] Restless legs syndrome/Willis-Ekbom disease in patients with Parkinson's disease
Minar, M.
Tosecka, R.
Valkovic, P.
EUROPEAN JOURNAL OF NEUROLOGY, 2016, 23 : 481 - 481
[46] Restless legs syndrome in Parkinson's disease Clinical characteristics and biochemical correlations
Guerreiro, Tiago Machado
Candido Nishikawa, Danilo Ryuko
Ferreira, Lis Campos
de Melo, Hyder Aragao
Pereira do Prado, Roberto Cesar
ARQUIVOS DE NEURO-PSIQUIATRIA, 2010, 68 (06) : 869 - 872
[47] Restless Legs Syndrome and Its Associated Risk Factors in Parkinson's Disease
Azmin, Shahrul
Anuar, Abdul Manaf Khairul
Nafisah, Wan Yahya
Tan, Hui Jan
Raymond, Azman Ali
Hanita, Othman
Shah, Shamsul Azhar
Norlinah, Mohamed Ibrahim
PARKINSONS DISEASE, 2013, 2013
[48] Nocturnal subcutaneous apomorphine infusion in Parkinson's disease and restless legs syndrome
Reuter, I
Ellis, CM
Chaudhuri, KR
ACTA NEUROLOGICA SCANDINAVICA, 1999, 100 (03): : 163 - 167
[49] A study to look for the incidence or restless legs syndrome in patients with Parkinson's disease
Khan, SA
Sahota, PK
SLEEP, 2002, 25 : A378 - A379
[50] Event-related potentials in Restless Legs Syndrome and Parkinson's disease
Poceta, J.
Houser, M.
Polich, J.
SLEEP, 2006, 29 : A274 - A274

← 1 2 3 4 5 →