The diagnostic assessment of tumor extent, grading and detection of recurrence of brain tumors remains a challenge in the era of magnetic resonance imaging (MRI). Positron emission tomography (PET) and single photon emission computed tomography (SPECT) may provide relevant additional information which allow more accurate diagnostics in unclear situations. Especially, PET and SPECT studies using radiolabeled amino acids offer a better delineation of cerebral gliomas which helps to guide biopsies, to plan surgical interventions and radiation therapy. Additionally, several radiotracers help to differentiate tumor recurrence from unspecific post-therapeutic changes in brain tissue and provide information on histological grading and prognosis of brain tumors.
机构:
Max Planck-Inst. for Neurol. Res., University of Cologne
Center for Molecular Medicine (CMMC), University of Cologne
Department of Neurology, University of Cologne
Department of Neurology, University of Cologne, MPI for Neurological Research, 50931 CologneMax Planck-Inst. for Neurol. Res., University of Cologne
Jacobs A.H.
Kracht L.W.
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Max Planck-Inst. for Neurol. Res., University of CologneMax Planck-Inst. for Neurol. Res., University of Cologne
Kracht L.W.
Gossmann A.
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Department of Radiology, University of CologneMax Planck-Inst. for Neurol. Res., University of Cologne
Gossmann A.
Rüger M.A.
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Max Planck-Inst. for Neurol. Res., University of Cologne
Center for Molecular Medicine (CMMC), University of CologneMax Planck-Inst. for Neurol. Res., University of Cologne
Rüger M.A.
Thomas A.V.
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Department of Neurology, University of CologneMax Planck-Inst. for Neurol. Res., University of Cologne
Thomas A.V.
Thiel A.
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Max Planck-Inst. for Neurol. Res., University of Cologne
Department of Neurology, University of CologneMax Planck-Inst. for Neurol. Res., University of Cologne
Thiel A.
Herholz K.
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Department of Neurology, University of CologneMax Planck-Inst. for Neurol. Res., University of Cologne