Probing the Motion of the Intrinsically Disordered Neuronal Protein Alpha-Synuclein through the VDAC Pore using a Single-Molecule Approach

被引:0
|
作者
Hoogerheide, David P. [1 ,2 ]
Gurnev, Philip A. [1 ,3 ]
Rostovtseva, Tatiana K. [1 ]
Bezrukov, Sergey M. [1 ]
机构
[1] Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, NIH, Bethesda, MD USA
[2] NIST, Ctr Neutron Res, Gaithersburg, MD 20899 USA
[3] Univ Massachusetts, Dept Phys, Amherst, MA 01003 USA
关键词
D O I
10.1016/j.bpj.2014.11.1025
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
933-Plat
引用
收藏
页码:185A / 185A
页数:1
相关论文
共 50 条
  • [41] Probing Surface Hydrophobicity of Individual Protein at Single-Molecule Resolution using Solid-State Nanopores
    Li, Ji
    BIOPHYSICAL JOURNAL, 2016, 110 (03) : 336A - 336A
  • [42] Mass-Independent, High-Fidelity Single-Molecule Differentiation using the Aerolysin Protein Pore
    Ensslen, Tobias
    Ouldali, Hadjer
    Oukhaled, Abdelghani
    Behrends, Jan C.
    BIOPHYSICAL JOURNAL, 2020, 118 (03) : 474A - 475A
  • [43] Probing single-molecule DNA-protein interactions using ABEL-FRET and ABEL-PIFE
    Wang, Quan
    BIOPHYSICAL JOURNAL, 2023, 122 (03) : 430A - 430A
  • [44] Probing Membrane Protein Interactions with Their Lipid Raft Environment Using Single-Molecule Tracking and Bayesian Inference Analysis
    Tuerkcan, Silvan
    Richly, Maximilian U.
    Alexandrou, Antigoni
    Masson, Jean-Baptiste
    PLOS ONE, 2013, 8 (01):
  • [45] Nonadiabatic vibronic effects in single-molecule junctions: A theoretical study using the hierarchical equations of motion approach
    Kaspar, C.
    Erpenbeck, A.
    Baetge, J.
    Schinabeck, C.
    Thoss, M.
    PHYSICAL REVIEW B, 2022, 105 (19)
  • [46] High-Density Single-Layer Coating of Gold Nanoparticles onto Multiple Substrates by Using an Intrinsically Disordered Protein of α-Synuclein for Nanoapplications
    Bhak, Ghibom
    Lee, Junghee
    Kim, Chang-Hyun
    Chung, Dong Young
    Kang, Jin Hyoun
    Oh, Soojung
    Lee, Jungsup
    Kang, Jin Soo
    Yoo, Ji Mun
    Yang, Jee Eun
    Rhoo, Kun Yil
    Park, Sunghak
    Lee, Somin
    Nam, Ki Tae
    Jeon, Noo Li
    Jang, Jyongsik
    Hong, Byung Hee
    Sung, Yung-Eun
    Yoon, Myung-Han
    Paik, Seung R.
    ACS APPLIED MATERIALS & INTERFACES, 2017, 9 (10) : 8519 - 8532
  • [47] Alpha-Synuclein Repression Using Zinc Finger Protein Transcription Factors - A Novel Therapeutic Approach for the Treatment of Parkinson's Disease
    Hatami, Asa
    Hoang-Oanh Nguyen
    Roth, Theresa
    Yu, Qi
    Marlen, Kimberly
    Paschon, David
    Mutter-Rottmayer, Elizabeth
    Van, Ken
    Ledeboer, Annmarie
    Phillips, Angelica
    Lu, Yanmei
    Tait, Emily
    Lam, Stephen
    Hinkley, Sarah
    Goodwin, Alicia
    Surosky, Richard
    Rebar, Edward J.
    Meyer, Kathleen
    Zeitler, Bryan
    Pooler, Amy M.
    MOLECULAR THERAPY, 2021, 29 (04) : 264 - 265
  • [48] Observing Single-Molecule Protein-DNA Interactions and DNA Transcription In Vitro using Transcriptomic Tethered Particle Motion
    Visser, Emilius
    Miladinovic, Jovana
    Milstein, Joshua
    BIOPHYSICAL JOURNAL, 2020, 118 (03) : 490A - 490A
  • [49] Studying protein transport and adsorption/desorption kinetics on ion-exchange adsorbents using a single-molecule approach
    Poongavanam, Mohan
    Kisley, Lydia
    Mansur, Andrea
    Chen, Jixin
    Kourentzi, Katerina
    Chen, Wen-Hsiang
    Dhamane, Sagar
    Landes, Christy
    Willson, Richard
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2013, 245
  • [50] Levels of plasma alpha-synuclein as measured using Single Molecule Array technology is higher in Parkinson's disease compared to controls and is not influenced by LRRK2 genotype
    Tan, Y. J.
    Ng, A.
    Lu, Z. H.
    Ng, S.
    Ng, E.
    Setiawan, F.
    Au, W. L.
    Tan, E. K.
    Tan, L.
    MOVEMENT DISORDERS, 2018, 33 : S636 - S637