Biodegradation of PLA-Pennisetum purpureum based biocomposite scaffold

被引：8
|
作者：
Revati, R. [1 ]
Majid, M. S. Abdul [1 ]
Ridzuan, M. J. M. [1 ]
Normahira, M. [1 ]
Nasir, N. F. Mohd [1 ]
Cheng, E. M. [1 ]
机构：
[1] Univ Malaysia Perlis, Kampus Tetap Pauh Putra, Pauh 02600, Perlis, Malaysia
来源：
INTERNATIONAL CONFERENCE ON APPLICATIONS AND DESIGN IN MECHANICAL ENGINEERING (ICADME 2017) | 2017年 / 908卷
关键词：
IN-VITRO DEGRADATION; TISSUE; FIBER; BEHAVIOR; FUNCTIONALIZATION; BONE;
D O I：
10.1088/1742-6596/908/1/012029
中图分类号：
TH [机械、仪表工业];
学科分类号：
0802 ;
摘要：
The in vitro degradation and mechanical properties of a 3D porous Pennisetum purpureum (PP)/polylactic acid (PLA). based scaffold was investigated. In this study, composite scaffolds with PP to PLA ratio of 0%, 10%, 20%, and 30% were immersed in PBS solution at 37 degrees C for 40 days. Interestingly, the degradation rate was reduced for the PLA/PP20 scaffold, though insignificantly, this could be attributed to the improved mechanical properties and stronger fibre-matrix interface. The FESEM results indicated that a sound fibre-matrix interface was formed in the PLA/PP20 scaffold, which reflected the addition of P. purpureum into PLA decreasing the degradation rate compared to in pure PLA scaffolds. The results suggest that the P. purpureum/PLA scaffold degradation rate can be altered and controlled to meet the requirement imposed by a given tissue engineering application.
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收藏
页数：7
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