Colchicine use in children and adolescents with familial Mediterranean fever: Literature review and consensus statement

被引：180

作者：

Kallinich, Tilmann

Haffner, Dieter

Niehues, Tim

Huss, Kristina

Lainka, Elke

Neudorf, Ulrich

Schaefer, Christof

Stojanov, Silvia

Timmann, Christian

Keitzer, Rolf

Ozdogan, Huri

Ozen, Seza

机构：

[1] Univ Med Berlin, Dept Pediat Pneumol & Immunol, Berlin, Germany

[2] Univ Hosp Rostock, Dept Pediat, Rostock, Germany

[3] Univ Dusseldorf, Dept Pediat Oncol Hematol & Immunol, D-4000 Dusseldorf, Germany

[4] Univ Duisburg Gesamthsch, Dept Pediat, D-4100 Duisburg, Germany

[5] Childrens Univ Hosp, Dept Infect Dis & Immunol, Munich, Germany

[6] Berliner Betrieb Zent Gesundheitl Aufugaben, Berlin, Germany

[7] Bernhard Nocht Inst Trop Med, Dept Mol Med, Hamburg, Germany

[8] Istanbul Univ, Cerrahpasa Med Sch, Cerrahpasa, Turkey

[9] Hacettepe Univ, Fac Med, Dept Pediat Nephrol & Rheumatol, Ankara, Turkey

来源：

PEDIATRICS | 2007年 / 119卷 / 02期

关键词：

familial Mediterranean fever; colchicine; evidence-based guidelines; treatment;

D O I：

10.1542/peds.2006-1434

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

The daily application of colchicine is the standard therapy for prophylaxis of attacks and amyloid deposition in familial Mediterranean fever. However, because of many issues (eg, dosage, time of introduction, etc), no standardized treatment recommendations have been established. In this work we review the available literature on colchicine use with respect to its indication, efficacy, mode of application, and safety in children and adolescents with familial Mediterranean fever. On the basis of this analysis, a consensus statement on the application of colchicine in children and adolescents with familial Mediterranean fever was developed by caregivers from Germany, Austria, and Turkey.

引用

页码：E474 / E483

页数：10

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