Inhibition of both c-Met and EGFR signaling shows synergistic antitumor activity in non-small cell lung cancer model

被引:1
|
作者
Tammam, Jennifer G.
Davis, Lenora
Ware, Chris
Reilly, John F.
Deshmukh, Sujal V.
Dinsmore, Christopher
Marshall, Gary
Harrington, Elizabeth A.
Pan, Bo-Sheng
Lutterbach, Bart A.
Majumder, Pradip K.
机构
关键词
D O I
10.1158/1535-7163.TARG-09-C209
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
C209
引用
收藏
页数:2
相关论文
共 50 条
  • [41] Association of integrin beta1 and c-MET in mediating EGFR TKI gefitinib resistance in non-small cell lung cancer
    Ju, Lixia
    Zhou, Caicun
    CANCER CELL INTERNATIONAL, 2013, 13
  • [42] Efficacy and safety of MCLA-129, an EGFR/c-MET bispecific antibody, in advanced non-small cell lung cancer (NSCLC)
    Wang, Jie
    Zhong, Jia
    Wu, Lin
    Chen, Bolin
    Wang, Zhe-Hai
    Yao, Yu
    Dong, Xiaorong
    Li, Wei
    Ren, Xiubao
    Hou, Xiaoming
    Zang, Ai-min
    Qu, Xiujuan
    Zhang, Guojun
    Wang, Yongsheng
    Bai, Yuansong
    Liu, Linlin
    Yu, Guohua
    Chen, Xingwu
    Ding, Lieming
    JOURNAL OF CLINICAL ONCOLOGY, 2024, 42 (16)
  • [43] Mechanism of c-Met and EGFR tyrosine kinase inhibitor resistance through epithelial mesenchymal transition in non-small cell lung cancer
    Rastogi, Ichwaku
    Rajanna, Supriya
    Webb, Andrew
    Chhabra, Gagan
    Foster, Brad
    Webb, Brian
    Puri, Neelu
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2016, 477 (04) : 937 - 944
  • [44] Plasma dynamic monitoring of soluble c-Met level for EGFR-TKI treatment in advanced non-small cell lung cancer
    Gao, H-F.
    Wu, Y-L.
    Yang, J-J.
    Zhang, X-C.
    JOURNAL OF THORACIC ONCOLOGY, 2016, 11 (04) : S125 - S125
  • [45] Clinical Pharmacology of EGFR/Met Inhibitors in Non-Small Cell Lung Cancer
    Yagishita, Shigehiro
    Hamada, Akinobu
    CURRENT DRUG TARGETS, 2014, 15 (14) : 1263 - 1272
  • [46] Analysis of C-MET Amplification Non-Small Cell Lung Cancer Cell Blocks from Pleural Effusion
    Xu, C.
    Wang, W.
    Zhuang, W.
    Chen, G.
    Tian, Y.
    Xu, J.
    Fang, M.
    Lv, T.
    Song, Y.
    JOURNAL OF THORACIC ONCOLOGY, 2017, 12 (11) : S1944 - S1945
  • [47] Strengthening Context-Dependent Anticancer Effects on Non-Small Cell Lung Carcinoma by Inhibition of Both MET and EGFR
    Zhang, Yu-Wen
    Staal, Ben
    Essenburg, Curt
    Lewis, Steven
    Kaufman, Dafna
    Vande Woude, George F.
    MOLECULAR CANCER THERAPEUTICS, 2013, 12 (08) : 1429 - 1441
  • [48] Improved diagnostics targeting c-MET in non-small cell lung cancer: expression, amplification and activation?
    I. Watermann
    B. Schmitt
    F. Stellmacher
    J. Müller
    R. Gaber
    Ch. Kugler
    N. Reinmuth
    R. M. Huber
    M. Thomas
    P. Zabel
    K. F. Rabe
    D. Jonigk
    A. Warth
    E. Vollmer
    M. Reck
    T. Goldmann
    Diagnostic Pathology, 10
  • [49] Improved diagnostics targeting c-MET in non-small cell lung cancer: expression, amplification and activation?
    Watermann, I.
    Schmitt, B.
    Stellmacher, F.
    Mueller, J.
    Gaber, R.
    Kugler, Ch.
    Reinmuth, N.
    Huber, R. M.
    Thomas, M.
    Zabel, P.
    Rabe, K. F.
    Jonigk, D.
    Warth, A.
    Vollmer, E.
    Reck, M.
    Goldmann, T.
    DIAGNOSTIC PATHOLOGY, 2015, 10
  • [50] Correlation among genetic variations of c-MET in Chinese patients with non-small cell lung cancer
    Duan, Jianchun
    Yang, Xiaodan
    Zhao, Jun
    Zhuo, Minglei
    Wang, Zhijie
    An, Tongtong
    Bai, Hua
    Wang, Jie
    ONCOTARGET, 2018, 9 (02) : 2660 - 2667