Protein adsorption on solid surfaces

被引:407
|
作者
Hlady, V
Buijs, J
机构
[1] Center for Biopolymers at Interfaces, Department of Bioengineering, 108 Biomed. Poly. Research Building, Salt Lake City
关键词
D O I
10.1016/S0958-1669(96)80098-X
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The research field of protein adsorption on surfaces appears to be as popular as ever. In the past year, several hundred published papers tackled problems ranging from fundamental aspects of protein surface interactions to applied problems of surface blood compatibility and protein surface immobilization. Although some parts of the protein adsorption process, such as kinetics and equilibrium interactions, can be accurately predicted, other aspects, such as the extent and the rate of protein conformational change, are still somewhat uncertain. The whole field is ripe for a comprehensive theory on protein adsorption.
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页码:72 / 77
页数:6
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