Palladium-Catalyzed C-H Arylation of Amides by Triazole Assistance

被引：33
|
作者：
Santrac, Darko [1 ]
Cella, Stefano [1 ]
Wang, Wei [1 ]
Ackermann, Lutz [1 ]
机构：
[1] Georg August Univ, Inst Organ & Biomol Chem, Tammannstr 2, D-37077 Gottingen, Germany
来源：
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2016年 / 2016卷 / 32期
基金：
欧洲研究理事会;
关键词：
Synthetic methods; C-H activation; Amides; Palladium; Arenes; UNACTIVATED C(SP(3))-H BONDS; BENZOIC-ACID DERIVATIVES; DIRECTING GROUP; 1,2,3-TRIAZOLE AMINE; C(SP(2))-H BONDS; AROMATIC AMIDES; CLICK CHEMISTRY; ACTIVATION; ALKYLATION; SP(3);
D O I：
10.1002/ejoc.201601045
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Versatile palladium-catalyzed C-H arylations of benzamides were accomplished with the assistance of a removable triazole amine (TAM). The robustness of the palladium-catalyzed C-H functionalization protocol is reflected in its broad functional group tolerance, ample substrate scope, and ability to proceed under silver-free reaction conditions.
引用
收藏
页码：5429 / 5436
页数：8
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