Facile assembly of indeno[1,2-c]chromenes via a palladium-catalyzed reaction of 2-alkynylhalobenzene

被引：17
|
作者：
Pan, Xiaolin [2 ]
Nie, Hongming [1 ]
Luo, Yong [2 ]
Gao, Yueqiu [1 ]
Wu, Jie [2 ,3 ]
机构：
[1] Shanghai Univ TCM, Shanghai Shuguang Hosp, Dept Hepatol Dis, Shanghai 201203, Peoples R China
[2] Fudan Univ, Dept Chem, Shanghai 200433, Peoples R China
[3] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2012年 / 10卷 / 41期
基金：
中国国家自然科学基金;
关键词：
DIVERSITY-ORIENTED SYNTHESIS; 3-COMPONENT REACTION; CARBONYLATIVE ANNULATION; ORGANIC-SYNTHESIS; CASCADE REACTIONS; O-ALKYNYLPHENOLS; EFFICIENT; FORM; 2-ALKYNYLPHENOLS; 2-ALKYNYLANILINE;
D O I：
10.1039/c2ob26369f
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
2-Alkynylhalobenzene reacts with 2-alkynylphenol in the presence of a palladium catalyst, leading to indeno[1,2-c]chromenes in good to excellent yields. Furthermore, the scaffold of indeno[1,2-c]chromene could be constructed via a palladium-catalyzed reaction of 2-alkynylbromobenzene with water, in which four bonds are formed with high efficiency.
引用
收藏
页码：8244 / 8250
页数：7
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