Habitual fish consumption does not prevent a decrease in LCPUFA status in pregnant women (the Seychelles Child Development Nutrition Study)

被引:30
|
作者
Bonham, M. P. [1 ]
Duffy, E. M. [1 ]
Wallace, J. M. W. [1 ]
Robson, P. J. [1 ]
Myers, G. J. [2 ]
Davidson, P. W. [2 ]
Clarkson, T. W. [2 ]
Shamlaye, C. F.
Strain, J. J. [1 ]
机构
[1] Univ Ulster, Dept Biomed Sci, NICHE, Coleraine BT52 1SA, Londonderry, North Ireland
[2] Univ Rochester, Sch Med & Dent, Rochester, NY 14642 USA
来源
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS | 2008年 / 78卷 / 06期
关键词
D O I
10.1016/j.plefa.2008.04.005
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Information on the status of long-chain polyunsaturated fatty acids (LCPUFAs) in pregnancy and breast milk in very high fish-eating populations is limited. The aim of this study was to examine dietary intake and changes in fatty acid status in a population of pregnant women in the Republic of Seychelles. Serum docosahexaenoic acid (DHA) decreased significantly between 28-week gestation and delivery (n = 196). DHA status did not correlate significantly with length of gestation and was not associated with self-reported fish intake, which was high at 527 g/week. In breast milk, the ratio of DHA to arachidonic acid (AA) was consistent with those observed in other high fish-eating populations. Overall the data suggest that high exposure to LCPUFAs from habitual fish consumption does not prevent the documented decrease in LCPUFA status in pregnancy that occurs as a result of foetal accretion in the third trimester of pregnancy. (C) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码:343 / 350
页数:8
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