Design of macrocyclic serine protease inhibitors using a screen based on enzymatic cyclization.

被引：0

作者：

Haman, KK ^{[1
]}

Bartlett, P ^{[1
]}

机构：

[1] Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA

来源：

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 1999年 / 218卷

关键词：

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

380-ORGN

引用

页码：U127 / U127

页数：1

共 50 条

[31] Structure-based design of serine protease inhibitors:: Discovery of selective chymase inhibitors containing a novel β-amidophosphonic acid recognition motif
Hawkins, MJ
Greco, MN
Powell, ET
Corcoran, TW
De Garavilla, L
Kauffman, JA
Wang, Y
Minor, L
Di Cera, E
Sukumar, N
Chen, ZW
Pineda, AO
Mathews, FS
Maryanoff, BE
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2005, 230 : U2693 - U2693
[32] Design, synthesis, and biological activity of m-tyrosine-based 16-and 17-membered macrocyclic inhibitors of hepatitis C virus NS3 serine protease
Chen, KX
Njoroge, FG
Pichardo, J
Prongay, A
Butkiewicz, N
Yao, NH
Madison, V
Girijavallabhan, V
JOURNAL OF MEDICINAL CHEMISTRY, 2005, 48 (20) : 6229 - 6235
[33] IDENTIFICATION OF NOVEL NON-MACROCYCLIC INHIBITORS OF HCV NS3/4A SERINE PROTEASE ACTIVITY
Buckman, Brad O.
Pan, Lin
Huang, Lea
Kossen, Karl
Rajagopalan, Ravi
Misialek, Shawn
Stevens, Sarah K.
Tan, Hua
Ruhrmund, Donald
Serebryany, Vladimir
Matulik-Adamic, Jasenka
Stoycheva, Antitsa
Ammons, Steve
Fuhrer, Douglas K.
Blatt, Lawrence M.
Beigelman, Leo
Seiwert, Scott
HEPATOLOGY, 2008, 48 (04) : 1164A - 1165A
[34] Inhibition of human erythrocyte invasion by Babesia divergens using serine protease inhibitors
Montero, Estrella
Rafiq, Sarwish
Heck, Susanne
Lobo, Cheryl A.
MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 2007, 153 (01) : 80 - 84
[35] Identification and biochemical characterization of small molecule inhibitors of west nile virus serine protease by a high throughput screen
Padmanabhan, Radhakris
Mueller, Niklaus
Pattabiraman, Nagarajan
ANTIVIRAL RESEARCH, 2007, 74 (03) : A30 - A30
[36] Isosorbide-based peptidomimetics as inhibitors of hepatitis C virus serine protease
Portela, Aline C.
Barros, Thalita G.
Lima, Camilo H. da S.
Dias, Luiza R. S.
Azevedo, Pedro H. R. de A.
Dantas, Anna Sophia C. L.
Mohana-Borges, Ronaldo
Ventura, Gustavo T.
Pinheiro, Sergio
Muri, Estela M. F.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 27 (16) : 3661 - 3665
[37] Structure-based design and synthesis of triazole-based macrocyclic inhibitors of norovirus protease: Structural, biochemical, spectroscopic, and antiviral studies
Weerawarna, Pathum M.
Kim, Yunjeong
Kankanamalage, Anushka C. Galasiti
Damalanka, Vishnu C.
Lushington, Gerald H.
Alliston, Kevin R.
Mehzabeen, Nurjahan
Battaile, Kevin P.
Lovell, Scott
Chang, Kyeong-Ok
Groutas, William C.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 119 : 300 - 318
[38] An integrated approach to ligand- and structure-based drug design: Development and application to a series of serine protease inhibitors
Nicolotti, Orazio
Miscioscia, Teresa Fabiola
Carotti, Andrea
Leonetti, Francesco
Carotti, Angelo
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2008, 48 (06) : 1211 - 1226
[39] Design, synthesis, and evaluation of a novel series of macrocyclic inhibitors of norovirus 3CL protease
Damalanka, Vishnu C.
Kim, Yunjeong
Kankanamalage, Anushka C. Galasiti
Lushington, Gerald H.
Mehzabeen, Nurjahan
Battaile, Kevin P.
Lovell, Scott
Chang, Kyeong-Ok
Groutas, William C.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 127 : 41 - 61
[40] Design of Specific Serine Protease Inhibitors Based on a Versatile Peptide Scaffold: Conversion of a Urokinase Inhibitor to a Plasma Kallikrein Inhibitor
Xu, Peng
Xu, Mingming
Jiang, Longguang
Yang, Qinglan
Luo, Zhipu
Dauter, Zbigniew
Huang, Mingdong
Andreasent, Peter A.
JOURNAL OF MEDICINAL CHEMISTRY, 2015, 58 (22) : 8868 - 8876

← 1 2 3 4 5 →