Cooperative group trials in pediatric oncology: The surgeon's role

被引：8
|
作者：
Shamberger, Robert C. [1 ,2 ]
机构：
[1] Childrens Hosp, Dept Surg, Boston, MA 02115 USA
[2] Harvard Univ, Sch Med, Boston, MA USA
来源：
JOURNAL OF PEDIATRIC SURGERY | 2013年 / 48卷 / 01期
关键词：
Children's Cancer Study Group; Intergroup Rhabdomyosarcoma Study; Pediatric Oncology Group; National Wilms Tumor Study Group; Cooperative group trials; Neuroblastoma; Wilms tumor; Rhabdomyosarcoma; Ewing's sarcoma; Osteosarcoma; NATIONAL WILMS-TUMOR; CHILDRENS CANCER GROUP; SARCOMA/PRIMITIVE NEUROECTODERMAL TUMOR; HIGH-RISK NEUROBLASTOMA; INTERGROUP RHABDOMYOSARCOMA; EWINGS-SARCOMA; RADIATION-THERAPY; PROGNOSTIC-SIGNIFICANCE; NEURO-BLASTOMA; STANDARD CHEMOTHERAPY;
D O I：
10.1016/j.jpedsurg.2012.10.068
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
The early history of the pediatric cooperative group trials is reviewed, and the surgeons who played a critical role in their formation are discussed. The vital information provided from the tumor specimens submitted as part of the protocols is presented, as well as how this information advanced our management of infants and children treated on current protocols of the Children's Oncology Group. Finally, a survey of the surgeons currently active in the clinical trials defined the "critical lessons" learned from the sequence of protocols by the cooperative groups which have advanced our surgical treatment of patients today. (C) 2013 Elsevier Inc. All rights reserved.
引用
收藏
页码：1 / 13
页数：13
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