Nigella sativa L. seed and seed oil: potential sources of high-value components for development of functional foods and nutraceuticals/pharmaceuticals

被引:34
|
作者
Mukhtar, Hamid [1 ]
Qureshi, Aminah Suhail [1 ]
Anwar, Farooq [2 ]
Mumtaz, Muhammad Waseem [3 ]
Marcu, Monica [4 ]
机构
[1] Govt Coll Univ, Inst Ind Biotechnol, Lahore, Pakistan
[2] Univ Sargodha, Dept Chem, Sargodha, Pakistan
[3] Univ Gujrat, Dept Chem, Gujrat, Pakistan
[4] AstaMed, Plant, Beauty, Med, Seattle, WA USA
关键词
Black cumin; thymoquinone; high-value nutrients; antioxidants; nutraceuticals; antimicrobial; black seed; BLACK CUMIN; CHEMICAL-COMPOSITION; ANTIOXIDANT ACTIVITY; NUTRITIONAL-VALUE; OXIDATIVE STRESS; FIXED OIL; THYMOQUINONE; CELLS; ANTICONVULSANT; TOCOPHEROL;
D O I
10.1080/10412905.2018.1562388
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Black cumin (Nigella sativa L., Kalonji), is a well-known medicinal food plant with a long history of ethno-medicinal uses. Its active ingredients are mainly concentrated in the essential oil of the seed. The plant has been widely used as an analgesic, anti-inflammatory, anticancer, antimicrobial, antioxidant and gastro-protective agent. It has been demonstrated that the therapeutic properties of N. sativa are due to the presence of thymoquinone, a major biologically active constituent of the essential oil, along with other high-value components such as linoleic acid, nigellone (dithymoquinone), nigilline, melanthin, and trans-anethole. The present review mainly focuses on the detailed phytochemical, nutritional, and therapeutic aspects of the seed and seed oil of N. sativa so as to explore their potential applications for the development of innovative functional foods, nutraceuticals, and pharmaceuticals as well as to help establish the scientific basis for the widespread traditional medicinal uses of this multipurpose spice.
引用
收藏
页码:171 / 183
页数:13
相关论文
共 50 条
  • [31] An investigation of physicochemical properties of Nigella sativa L. Seed oil from Al-Qassim by different extraction methods
    Alrashidi, Moneer
    Derawi, Darfizzi
    Salimon, Jumat
    Yusoff, Mohamad Firdaus
    JOURNAL OF KING SAUD UNIVERSITY SCIENCE, 2020, 32 (08) : 3337 - 3342
  • [32] A Comprehensive Review of the Antioxidant, Antimicrobial, and Therapeutic Efficacies of Black Cumin (Nigella sativa L.) Seed Oil and Its Thymoquinone
    Chatterjee, Gourab
    Saha, Asit Kumar
    Khurshid, Shamama
    Saha, Achintya
    JOURNAL OF MEDICINAL FOOD, 2025,
  • [33] Effects of different nitrogen doses on thymoquinone and fatty acid composition in seed oil of black cumin (Nigella sativa L.)
    Telci, Isa
    Izgi, Mehmet Necat
    Ozek, Temel
    Yasak, Selma
    Yur, Suleyman
    Ozek, Gulmira
    JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 2022, 99 (03) : 229 - 237
  • [34] High-Performance Liquid Chromatography Quantification of Principal Antioxidants in Black seed (Nigella sativa L.) Phytopharmaceuticals
    Hadad, Ghada M.
    Salam, Randa A. Abdel
    Soliman, Rabab M.
    Mesbah, Mostafa K.
    JOURNAL OF AOAC INTERNATIONAL, 2012, 95 (04) : 1043 - 1047
  • [35] USE OF BLACK SEED (NIGELLA SATIVA L.) OIL IN THE MANAGEMENT OF HYPERTENSIVE AND HYPERLIPIDEMIC INDIVIDUALS OF DISTRICT MUZAFFARABAD, AZAD KASHMIR, PAKISTAN
    Hussain, N.
    Majid, S. A.
    Abbasi, M. S.
    Hussain, M. A.
    Rehman, K.
    Khan, M. Q.
    Dar, M. E. U. I.
    Shaheen, H.
    Habib, T.
    APPLIED ECOLOGY AND ENVIRONMENTAL RESEARCH, 2017, 15 (04): : 31 - 48
  • [36] The Effects of Different Extraction Methods on Antioxidant Properties, Chemical Composition, and Thermal Behavior of Black Seed (Nigella sativa L.) Oil
    Mohammed, Nameer Khairullah
    Abd Manap, Mohd Yazid
    Tan, Chin Ping
    Muhialdin, Belal J.
    Alhelli, Amaal M.
    Hussin, Anis Shobirin Meor
    EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2016, 2016
  • [37] Efficient extraction of black cumin (Nigella sativa L.) seed oil containing thymol, using liquefied dimethyl ether (DME)
    Subratti, Afraz
    Lalgee, Lorale J.
    Jalsa, Nigel K.
    JOURNAL OF FOOD PROCESSING AND PRESERVATION, 2019, 43 (04)
  • [38] Response of Seed Yield and Essential oil of Black Cumin (Nigella sativa L.) Affected as Foliar Spraying of Nano-fertilizers
    Rezaei-Chiyaneh, Esmaeil
    Rahimi, Sajjad
    Rahimi, Amir
    Hadi, Hashem
    Mahdavikia, Hassan
    JOURNAL OF MEDICINAL PLANTS AND BY-PRODUCTS-JMPB, 2018, 7 (01): : 33 - 40
  • [39] Microcapsules of Sacha Inchi seed oil (Plukenetia volubilis L.) obtained by spray drying as a potential ingredient to formulate functional foods
    Rodriguez-Cortina, A.
    Hernandez-Carrion, M.
    FOOD RESEARCH INTERNATIONAL, 2023, 170
  • [40] Development Liquid and Solid Self Microemulsifying Drug Delivery System (L-SMEDDS and S-SMEDDS) Containing Black Seed Oil (Nigella sativa L.)
    Priani, Sani Ega
    Maulidina, Septiani Siti
    Darusman, Fitrianti
    JOURNAL OF PHARMACEUTICAL RESEARCH INTERNATIONAL, 2020, 32 (37) : 7 - 13