Photodynamic therapy-a promising treatment of oral mucosal infections

被引：5

作者：

Chen, Ting ^{[1
]}

Yang, Dan ^{[1
]}

Lei, Shangxue ^{[1
]}

Liu, Jiaxin ^{[1
]}

Song, Yansong ^{[1
]}

Zhao, Hang ^{[1
]}

Zeng, Xin ^{[1
]}

Dan, Hongxia ^{[1
]}

Chen, Qianming ^{[1
]}

机构：

[1] Sichuan Univ, Chinese Acad Med Sci, State Key Lab Oral Dis,West China Hosp Stomatol, Natl Clin Res Ctr Oral Dis,Res Unit Oral Carcinog, Chengdu 610041, Sichuan, Peoples R China

来源：

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY | 2022年 / 39卷

基金：

中国国家自然科学基金;

关键词：

Photodynamic therapy; Photosensitizer; Oral mucosa; Infection; Drug resistance; MULTIDRUG EFFLUX PUMPS; STAPHYLOCOCCUS-AUREUS; CANDIDA-ALBICANS; IN-VIVO; 5-AMINOLEVULINIC ACID; BIOFILM FORMATION; N-ACETYLCYSTEINE; DRUG-RESISTANCE; INACTIVATION; PHOTOSENSITIZERS;

D O I：

10.1016/j.pdpdt.2022.103010

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The treatment of oral mucosal infections is increasingly challenging owing to antibiotic resistance. Therefore, alternative antimicrobial strategies are urgently required. Photodynamic therapy (PDT) has attracted attention for the treatment of oral mucosal infections because of its ability to effectively inactivate drug-resistant bacteria, completely heal clinical infectious lesions and usually offers only mild adverse reactions. This review briefly summarizes relevant scientific data and published papers and discusses the potential mechanism and application of PDT in the treatment of oral mucosal infections.

引用

页数：11

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