Inhibition of Camp-Dependent PKA Activates β2-Adrenergic Receptor Stimulation of Cytosolic Phospholipase A2 via Raf-1/Mek/Erk and Ip3-Dependent Ca2+ Signaling in Atrial Myocytes

被引:0
|
作者
Pabbidi, Malikarjuna R. [1 ]
Mignery, Gregory A. [1 ]
Maxwell, Joshua T. [1 ]
Samarel, Alan M. [1 ]
de Tombe, Pieter P. [1 ]
Lipsius, Stephen L. [1 ]
机构
[1] Loyola Univ Chicago, Maywood, IL USA
关键词
D O I
10.1016/j.bpj.2013.11.1769
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
引用
收藏
页码:305A / 305A
页数:1
相关论文
共 48 条
  • [21] Gamma-aminobutyric acid (GABA) inhibits cholangiocarcinoma growth by cAMP-dependent inhibition of the PKA/Src/MEK/ERK1/2 pathway.
    Fava, G
    Phinizy, JL
    Glaser, S
    Francis, H
    Marucci, L
    Benedetti, A
    Baumann, B
    Taffetani, S
    Venter, J
    Alpini, G
    HEPATOLOGY, 2003, 38 (04) : 680A - 680A
  • [22] Histamine stimulates the proliferation of small and large cholangiocytes by activation of both IP3/Ca2+ and cAMP-dependent signaling mechanisms
    Francis, Heather L.
    DeMorrow, Sharon
    Franchitto, Antonio
    Venter, Julie K.
    Mancinelli, Romina A.
    White, Mellanie A.
    Meng, Fanyin
    Ueno, Yoshiyuki
    Carpino, Guido
    Renzi, Anastasia
    Baker, Kimberly K.
    Shine, Hannah E.
    Francis, Taylor C.
    Gaudio, Eugenio
    Alpini, Gianfranco D.
    Onori, Paolo
    LABORATORY INVESTIGATION, 2012, 92 (02) : 282 - 294
  • [23] IP3-induced cytosolic and nuclear Ca2+ signals in HL-1 atrial myocytes: Possible role of IP3 receptor subtypes
    Kim, Joon-Chul
    Son, Min-Jeong
    Subedi, Krishna P.
    Kim, Do Han
    Woo, Sun-Hee
    MOLECULES AND CELLS, 2010, 29 (04) : 387 - 395
  • [24] IP3-INDUCED CYTOSOLIC AND NUCLEAR Ca2+ SIGNALS IN HL-1 ATRIAL MYOCYTES: POSSIBLE ROLE OF IP3 RECEPTOR SUBTYPES
    Woo, Sun-Hee
    Kim, Joon-Chul
    Son, Min-Jeong
    Kim, Do Han
    Subedi, Krishna P.
    JOURNAL OF PHYSIOLOGICAL SCIENCES, 2009, 59 : 238 - 238
  • [25] The growth of two human cholangiocarcinoma cell lines is inhibited by alpha-2 adrenergic agonists by a cAMP-dependent mechanism through the inhibition of Raf-1 and MAPK systems.
    Kanno, N
    Lesage, G
    Glaser, S
    Phinizy, JL
    Francis, H
    Ludvik, M
    Alpini, G
    GASTROENTEROLOGY, 2001, 120 (05) : A92 - A92
  • [26] Prostaglandin E2 activates cAMP response element-binding protein in glioma cells via a signaling pathway involving PKA-dependent inhibition of ERK
    Bidwell, Philip
    Joh, Kiwon
    Leaver, H. Anne
    Rizzo, Maria Teresa
    PROSTAGLANDINS & OTHER LIPID MEDIATORS, 2010, 91 (1-2) : 18 - 29
  • [27] CGMP inhibits IP3-induced Ca2+ release in intact rat megakaryocytes via cGMP- and cAMP-dependent protein kinases
    Tertyshnikova, X
    Yan, XW
    Fein, A
    JOURNAL OF PHYSIOLOGY-LONDON, 1998, 512 (01): : 89 - 96
  • [28] ACETYLCHOLINE ELICITS A REBOUND STIMULATION OF CA2+ CURRENT MEDIATED BY PERTUSSIS-TOXIN-SENSITIVE G-PROTEIN AND CAMP-DEPENDENT PROTEIN-KINASE-A IN ATRIAL MYOCYTES
    WANG, YG
    LIPSIUS, SL
    CIRCULATION RESEARCH, 1995, 76 (04) : 634 - 644
  • [29] α-1 adrenergic receptor agonists modulate ductal secretion of BDL rats via Ca2+- and PKC-dependent stimulation of cAMP
    LeSage, GD
    Alvaro, D
    Glaser, S
    Francis, H
    Marucci, L
    Roskams, T
    Phinizy, JL
    Marzioni, M
    Benedetti, A
    Taffetani, S
    Barbaro, B
    Fava, G
    Ueno, Y
    Alpini, G
    HEPATOLOGY, 2004, 40 (05) : 1116 - 1127
  • [30] Endothelin 1 Stimulates Ca2+-Sparks and Oscillations in Retinal Arteriolar Myocytes via IP3R and RyR-Dependent Ca2+ Release
    Tumelty, James
    Hinds, Kevin
    Bankhead, Peter
    McGeown, Neil J.
    Scholfield, C. Norman
    Curtis, Tim M.
    McGeown, J. Graham
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2011, 52 (06) : 3874 - 3879