The Effect of the Length of Histone H3K4me3 on Recognition by Reader Proteins

被引：7
|
作者：
Pieters, Bas [1 ]
Belle, Roman [1 ]
Mecinovic, Jasmin [1 ]
机构：
[1] Radboud Univ Nijmegen, Inst Mol & Mat, NL-6525 AJ Nijmegen, Netherlands
来源：
CHEMBIOCHEM | 2013年 / 14卷 / 18期
关键词：
histone; isothermal titration calorimetry; molecular recognition; protein-protein interactions; trimethyllysine; METHYLATION; H3;
D O I：
10.1002/cbic.201300525
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Thermodynamic analyses of associations between reader domain proteins and histone H3K4me3 peptides demonstrated that the shortest recognised histone substrate contains just the first four amino acids in histone 3. Deletion or addition at the N terminus resulted in a substantial decrease of binding affinity for most readers, thus verifying the importance of the H3A1 binding pocket. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码：2408 / 2412
页数：5
相关论文
共 50 条
  • [21] Histone Modifications of H3K4me3, H3K9me3 and Lineage Gene Expressions in Chimeric Mouse Embryo
    Salimi, Maryam
    Shirazi, Abolfazl
    Norouzian, Mohsen
    Mehrazar, Mohammad Mehdi
    Naderi, Mohammad Mehdi
    Shokrgozar, Mohammad Ali
    Omrani, Mirdavood
    Hashemi, Seyed Mahmoud
    CELL JOURNAL, 2020, 22 (01) : 96 - 105
  • [22] Histone H3K4me3 and H3K27me3 regulatory genes control stable transmission of an epimutation in rice
    Xiangsong Chen
    Xiaoyun Liu
    Yu Zhao
    Dao-Xiu Zhou
    Scientific Reports, 5
  • [23] The Tumor Suppressor ING5 Is a Dimeric, Bivalent Recognition Molecule of the Histone H3K4me3 Mark
    Ormaza, Georgina
    Rodriguez, Jhon A.
    Ibanez de Opakua, Alain
    Merino, Nekane
    Villate, Maider
    Gorrono, Irantzu
    Rabano, Miriam
    Palmero, Ignacio
    Vilaseca, Marta
    Kypta, Robert
    Vivanco, Maria D. M.
    Rojas, Adriana L.
    Blanco, Francisco J.
    JOURNAL OF MOLECULAR BIOLOGY, 2019, 431 (12) : 2298 - 2319
  • [24] The Expression of PPARγ in Preeclampsia regulates the Histone Modifications H3K4me3 and H3K9ac
    Meister, S.
    Hahn, L.
    Beyer, S.
    Paul, C.
    Mitter, S.
    Kuhn, C.
    von Schoenfeldt, V
    Corradini, S.
    Sudan, K.
    Schulz, C.
    Kolben, T. M.
    Mahner, S.
    Jeschke, U.
    Kessler, M.
    Kolben, T.
    GEBURTSHILFE UND FRAUENHEILKUNDE, 2021, 81 (06) : E19 - E20
  • [25] A study on the relationship between arsenic exposure and H3K4me3 and H3K79me3 in human peripheral leukocyte histone
    严画竹
    ChinaMedicalAbstracts(InternalMedicine), 2018, 35 (04) : 205 - 206
  • [26] Thermal Manipulation During Embryogenesis Impacts H3K4me3 and H3K27me3 Histone Marks in Chicken Hypothalamus
    David, Sarah-Anne
    Carvalho, Anais Vitorino
    Gimonnet, Coralie
    Brionne, Aurelien
    Hennequet-Antier, Christelle
    Piegu, Benoit
    Crochet, Sabine
    Courousse, Nathalie
    Bordeau, Thierry
    Bigot, Yves
    Collin, Anne
    Coustham, Vincent
    FRONTIERS IN GENETICS, 2019, 10
  • [27] Histone Modification of H3K9me3, H4K20me3, H3K4me3 and H3K36me3 in Distal Bile Duct Cancer Correlate with Worse Prognosis
    Kim, Hangyeol
    Na, Kiyong
    Sung, Ji-Youn
    MODERN PATHOLOGY, 2020, 33 (SUPPL 2) : 1654 - 1654
  • [28] Histone Modification of H3K9me3, H4K20me3, H3K4me3 and H3K36me3 in Distal Bile Duct Cancer Correlate with Worse Prognosis
    Kim, Hangyeol
    Na, Kiyong
    Sung, Ji-Youn
    LABORATORY INVESTIGATION, 2020, 100 (SUPPL 1) : 1654 - 1654
  • [29] Transgenerational inheritance of mitochondrial hormetic oxidative stress mediated by histone H3K4me3 and H3K27me3 modifications
    Li, Yimin
    Wang, Chongyang
    Fu, Xiaoxia
    Wu, Dan
    He, Chenyang
    Dai, Wenyu
    Yue, Xiaoyang
    Luo, Zhenhuan
    Yang, Jing
    Wan, Qin-Li
    REDOX BIOLOGY, 2025, 82
  • [30] Global Histone H3 Lysine 4 Trimethylation (H3K4me3) Landscape Changes in Response to TGFβ
    Naik, Ankit
    Dalpatraj, Nidhi
    Thakur, Noopur
    EPIGENETICS INSIGHTS, 2021, 14
12345