Two new bioactive secondary metabolites from the endophytic fungus Talaromyces assiutensis JTY2

被引:9
|
作者
Li, Ying-Li [1 ,2 ]
Yi, Ji-Ling [1 ,2 ]
Cai, Jin [1 ,2 ]
Zhou, Xue-Ming [1 ,2 ]
Chen, Li [1 ,2 ]
Zhuo, Xin [1 ,2 ]
机构
[1] Hainan Normal Univ, Key Lab Trop Med Resource, Minist Educ, Coll Chem & Chem Engn, Haikou, Hainan, Peoples R China
[2] Hainan Normal Univ, Coll Chem & Chem Engn, Key Lab Trop Med Plant Chem Hainan Prov, Haikou, Hainan, Peoples R China
基金
中国国家自然科学基金;
关键词
Talaromyces assiutensis; lactone derivatives; pyrrolidine derivatives; antifungal; cytotoxic;
D O I
10.1080/14786419.2021.1881961
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
One new lactone derivative helicascolide F (1), one new pyrrolidine derivative talaromydine (2), along with six known compounds (3-8) were isolated from the fungus Talaromyces assiutensis JTY2. The structure of the new compounds 1 and 2 was determined by 1D and 2D NMR as well as by HRESIMS. The inhibitory activity of all compounds against six phytopathogenic fungi and three cancer cell lines was evaluated.
引用
收藏
页码:3695 / 3700
页数:6
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