Synthesis and crystal structure of ethyl (2-amino-4-(2-chlorophenyl)-4H-benzo-[h]-chromene-2-yl) formate

The title compound ethyl (2-amino-4-(2-chlorophenyl)-4H-benzo-[h]-chromene-2-yl) formate (C22H18ClNO3, Mr = 379.82) was synthesized and characterized by X-ray single-crystal diffraction analysis. The crystal belongs to monoclinic, space group C2/c with a = 25.168(4), b = 9.584(1), c 16.503(3)Angstrom, beta = 111.14(1)degrees, Z 8, V = 3713(1) Angstrom(3), D-c= 1.359 g/cm(3), mu(MoKalpha) = 0.228 mm(-1), F(000) = 1584, R = 0.0565 and wR = 0.1320 for 1749 observed reflections (I > 2sigma(I)). X-ray analysis reveals that the C(1), C(2), C(3), C(4), C(5) and 0(l) atoms form a six-membered ring which adopts a boat conformation. In this ring, the bond distances of C(1)-C(2) and C(4)-C(5) are 1.356(4) and 1.357(4) Angstrom, respectively, indicating they are C=C double bonds. In addition, there exist intra- and intermolecular hydrogen bonds in the crystal structure.