Hashimoto's Thyroiditis Concomitant with Sequential Autoimmune Hepatitis, Chorea and Polyserositis: A New Entity of Autoimmune Polyendocrine Syndrome?

被引：5

作者：

Yu, Haoyong ^{[1
]}

Qiu, Huiling ^{[2
]}

Pan, Jiemin ^{[1
]}

Wang, Shenqi ^{[1
]}

Bao, Yuqian ^{[1
]}

Jia, Weiping ^{[1
]}

机构：

[1] Shanghai Jiao Tong Univ, Affiliated Peoples Hosp 6, Shanghai Diabet Inst,Shanghai Clin Ctr Diabet, Dept Endocrinol & Metab,Shanghai Key Lab Diabet M, Shanghai, Peoples R China

[2] Shanghai Jiao Tong Univ, Affiliated Peoples Hosp 6, Dept Osteoporosis, Shanghai, Peoples R China

来源：

INTERNAL MEDICINE | 2013年 / 52卷 / 02期

关键词：

autoimmune polyglandular syndrome; Hashimoto's thyroiditis; autoimmune hepatitis; glucocorticoids; CHRONIC ACTIVE HEPATITIS; DISEASE; AUTOANTIBODIES;

D O I：

10.2169/internalmedicine.52.6799

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We herein report a case of Hashimoto's thyroiditis (HT) with sequential autoimmune hepatitis (AIH), chorea and polyserositis. The patient was a 24-year-old man who underwent subtotal thyroidectomy due to compression symptoms caused by goiter and was diagnosed with HT postoperatively based on pathological examinations two years previously. He had exhibited liver dysfunction and intermittent chorea since 2008. His liver function and polyserositis improved remarkably following the administration of ursodeoxycholic acid (UDCA) and methylprednisolone. This is a very rare case that can be classified as autoimmune polyglandular syndrome (APS) type 3. Early and adequate UDCA and glucocorticoid treatment may lead to a favorable prognosis.

引用

页码：255 / 258

页数：4

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