Momelotinib (MMB) Long-Term Safety: Pooled Data from Three Phase 3 Randomized-Controlled Trials (RCTs)

被引：1

作者：

Verstovsek, Srdan ^{[1
]}

Mesa, Ruben ^{[2
]}

Gupta, Vikas ^{[3
]}

Lavie, David ^{[4
]}

Dubruille, Viviane ^{[5
]}

Cambier, Nathalie ^{[6
]}

Platzbecker, Uwe ^{[7
]}

Hus, Marek ^{[8
]}

Xicoy, Blanca ^{[9
]}

Oh, Stephen T. ^{[10
]}

Kiladjian, Jean-Jacques ^{[11
]}

Vannucchi, Alessandro M. ^{[12
]}

Gerds, Aaron T. ^{[13
]}

Egyed, Miklos ^{[14
]}

Mayer, Jiri ^{[15
,16
]}

Sacha, Tomasz ^{[17
]}

Kawashima, Jun ^{[18
]}

Morris, Marc ^{[18
]}

Huang, Mei ^{[18
]}

Harrison, Claire ^{[19
]}

机构：

[1] Univ Texas MD Anderson Canc Ctr, Leukemia Dept, Houston, TX 77030 USA

[2] UT Hlth San Antonio Canc Ctr, San Antonio, TX USA

[3] Univ Hlth Network, Div Med Oncol & Hematol, Toronto, ON, Canada

[4] Hadassah Hebrew Univ, Med Ctr, Jerusalem, Israel

[5] Nantes Univ Hosp, Hematol Dept, Nantes, France

[6] Hosp St Vincent Paul GHICL Lille, Lille, France

[7] Univ Leipzig, Dept Hematol Cell Therapy & Hemostaseol, Med Ctr, Leipzig, Germany

[8] Med Univ Lublin, Lublin, Poland

[9] Univ Autanoma Barcelona, Barcelona, Spain

[10] Washington Univ, Siteman Canc Ctr, Sch Med, St Louis, MO USA

[11] Univ Paris, Hop St Louis, AP HP, Ctr Invest Clin, Paris, France

[12] Univ Florence, Florence, Italy

[13] Cleveland Clin, Dept Hematol & Med Oncol, Taussig Canc Inst, Cleveland, OH USA

[14] Som Cty Mr Kaposi Gen Hosp, Kaposver, Hungary

[15] Masaryk Univ, Brno, Czech Republic

[16] Univ Hosp Brno, Brno, Czech Republic

[17] Jagiellonian Univ Hosp, Krakow, Poland

[18] Sierra Oncol Inc, San Mateo, CA USA

[19] Guys & St ThomasNHS Fdn Trust, London, England

来源：

BLOOD | 2022年 / 140卷

关键词：

D O I：

10.1182/blood-2022-162543

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：9670 / 9672

页数：3

共 50 条

[41] Pooled Analysis of Long-Term Survival Data From Phase II and Phase III Trials of Ipilimumab in Unresectable or Metastatic Melanoma
Schadendorf, Dirk
Hodi, F. Stephen
Robert, Caroline
Weber, Jeffrey S.
Margolin, Kim
Hamid, Omid
Patt, Debra
Chen, Tai-Tsang
Berman, David M.
Wolchok, Jedd D.
JOURNAL OF CLINICAL ONCOLOGY, 2015, 33 (17) : 1889 - U48
[42] Long-term Oncologic Outcomes of Laparoscopic Versus Open Surgery for Rectal Cancer A Pooled Analysis of 3 Randomized Controlled Trials
Ng, Simon S. M.
Lee, Janet F. Y.
Yiu, Raymond Y. C.
Li, Jimmy C. M.
Hon, Sophie S. F.
Mak, Tony W. C.
Leung, Wing Wa
Leung, Ka Lau
ANNALS OF SURGERY, 2014, 259 (01) : 139 - 147
[43] LONG-TERM (104 WEEK) SAFETY PROFILE OF APREMILAST, AN ORAL PHOSPHODIESTERASE 4 INHIBITOR, IN PATIENTS WITH PSORIATIC ARTHRITIS: POOLED SAFETY ANALYSIS OF THREE PHASE III, RANDOMISED, CONTROLLED TRIALS
Philip, Mease
Adewale, O. Adebajo
Dafna, D. Gladman
Juan, J. Gomez-Reino
Stephen, Hall
Arthur, Kavanaugh
Eric, Lespessailles
Georg, Schett
Komal, Shah
Lichen, Teng
Jurgen, Wollenhaupt
INTERNAL MEDICINE JOURNAL, 2016, 46 : 23 - 23
[44] Long-Term Outcomes After Left Main PCI: An Individual Patient-Data Pooled Analysis of 21 Randomized Controlled Trials
Yadav, Mayank
Smits, Pieter
von Birgelen, Clemens
Serruys, Patrick
Mehran, Roxana
Kirtane, Ajay Jayant
Mintz, Gary
Madhavan, Mahesh
Redfors, Bjorn
Crowley, Aaron
Liu, Mengdan
Leon, Martin
Stone, Gregg
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2019, 74 (13) : B383 - B383
[45] Secukinumab Demonstrates Consistent Safety over Long-Term Exposure (up to 3 years) in Patients with Active Ankylosing Spondylitis: Pooled Analysis of Three Phase 3 Trials
Deodhar, Atul A.
Baraliakos, Xenofon
Marzo-Ortega, Helena
Sieper, Joachim
Andersson, Mats
Porter, Brian
Fox, Todd
ARTHRITIS & RHEUMATOLOGY, 2017, 69
[46] SECUKINUMAB DEMONSTRATES CONSISTENT SAFETY OVER LONG-TERM EXPOSURE (UP TO 3 YEARS) IN PATIENTS WITH ACTIVE ANKYLOSING SPONDYLITIS: POOLED ANALYSIS OF THREE PHASE 3 TRIALS
Deodhar, A.
Baraliakos, X.
Marzo-Ortega, H.
Sieper, J.
Andersson, M.
Porter, B.
Fox, T.
ANNALS OF THE RHEUMATIC DISEASES, 2017, 76 : 340 - 341
[47] Apremilast, An Oral Phosphodiesterase 4 Inhibitor, Is Associated With Long-Term (52-Week) Improvements In Enthesitis and Dactylitis In Patients With Psoriatic Arthritis: Pooled Results From Three Phase 3, Randomized, Controlled Trials
Gladman, Dafna D.
Mease, Philip J.
Kavanaugh, Arthur
Adebajo, Adewale O.
Gomez-Reino, Juan J.
Wollenhaupt, Juergen
Cutolo, Maurizio
Schett, Georg
Lespessailles, Eric
Shah, Kamal
Hu, ChiaChi
Stevens, Randall M.
Edwards, Christopher J.
Birbara, Charles A.
ARTHRITIS AND RHEUMATISM, 2013, 65 : S347 - S347
[48] Safety and tolerability of cancer drugs studied in phase 3 randomized controlled trials (RCTs) over the last decade.
Ribnikar, Domen
Goldvaser, Hadar
Ocana, Alberto
Templeton, Arnoud J.
Seruga, Bostjan
Amir, Eitan
JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (15)
[49] APREMILAST, AN ORAL PHOSPHODIESTERASE 4 INHIBITOR, IS ASSOCIATED WITH LONG-TERM (104-WEEK) IMPROVEMENTS IN ENTHESITIS AND DACTYLITIS IN PATIENTS WITH PSORIATIC ARTHRITIS: POOLED RESULTS FROM THREE PHASE 3, RANDOMIZED, CONTROLLED TRIALS
Gladman, D.
Kavanaugh, A.
Adebajo, A.
Gomez-Reino, J.
Wollenhaupt, J.
Cutolo, M.
Schett, G.
Lespessailles, E.
McIlraith, M.
Hu, C.
Edwards, C.
Birbara, C.
Mease, P.
ANNALS OF THE RHEUMATIC DISEASES, 2015, 74 : 133 - 134
[50] Apremilast, an Oral Phosphodiesterase 4 Inhibitor, is Associated with Long-Term (52-Week) Improvements in Enthesitis and Dactylitis in Patients with Psoriatic Arthritis: Pooled Results from Three Phase 3, Randomized, Controlled Trials
Gladman, Dafna
Mease, Phillip
Kavanaugh, Arthur
Adebajo, Adewale
Gomez-Reino, Juan
Wollenhaupt, Juergen
Cutolo, Maurizio
Schett, Georg
Lespessailles, Eric
Shah, Kamal
Hu, ChiaChi
Stevens, Randall
Edwards, Christopher
Birbara, Charles
JOURNAL OF RHEUMATOLOGY, 2014, 41 (07) : 1449 - 1449

← 1 2 3 4 5 →