Blockade of adenosine diphosphate receptors P2Y12 and P2Y1 is required to inhibit platelet aggregation in whole blood under flow -: Response

被引:0
|
作者
Turner, NA [1 ]
Moake, JL [1 ]
McIntire, LV [1 ]
机构
[1] Rice Univ, Dept Bioengn, Houston, TX 77005 USA
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:4645 / 4646
页数:2
相关论文
共 50 条
  • [41] P2Y1 and P2Y12 receptors for ADP desensitize by distinct kinase-dependent mechanisms
    Hardy, AR
    Conley, PB
    Luo, JS
    Benovic, JL
    Poole, AW
    Mundell, SJ
    BLOOD, 2005, 105 (09) : 3552 - 3560
  • [42] The P2Y1 and P2Y12 receptors mediate autoinhibition of transmitter release in sympathetic innervated tissues
    Quintas, Clara
    Fraga, Sonia
    Goncalves, Jorge
    Queiroz, Gloria
    NEUROCHEMISTRY INTERNATIONAL, 2009, 55 (07) : 505 - 513
  • [43] Synergistic action between inhibition of P2Y12/P2Y1 and P2Y12/thrombin in ADP- and thrombin-induced human platelet activation
    Nylander, S
    Mattsson, C
    Ramström, S
    Lindahl, TL
    BRITISH JOURNAL OF PHARMACOLOGY, 2004, 142 (08) : 1325 - 1331
  • [44] The role of platelet P2Y12 receptors in inflammation
    Parker, William A. E.
    Storey, Robert F.
    BRITISH JOURNAL OF PHARMACOLOGY, 2024, 181 (04) : 515 - 531
  • [45] Monitoring platelet inhibition induced by P2Y12 receptor blockade:: A comparison of P2Y12 specific assays
    Angiolillo, Domiaick J.
    Desai, Bhaloo
    Hang, Yuan
    Charlton, Ronald
    Bernardo, Esther
    Shoemaker, Steven
    Zenni, Martin
    Guzman, Luis
    Gilmore, Paul
    Bass, Theodore A.
    Costa, Marco A.
    AMERICAN JOURNAL OF CARDIOLOGY, 2006, 98 (8A): : 205M - 206M
  • [46] Uridine Triphosphate Thio Analogues Inhibit Platelet P2Y12 Receptor and Aggregation
    Guenduez, Dursun
    Tanislav, Christian
    Sedding, Daniel
    Parahuleva, Mariana
    Santoso, Sentot
    Troidl, Christian
    Hamm, Christian W.
    Aslam, Muhammad
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2017, 18 (02)
  • [47] P2Y12 or P2Y1 inhibitors reduce platelet deposition in a microfluidic model of thrombosis while apyrase lacks efficacy under flow conditions
    Maloney, S. F.
    Brass, Lawrence F.
    Diamond, S. L.
    INTEGRATIVE BIOLOGY, 2010, 2 (04) : 183 - 192
  • [48] Adenosine diphosphate-induced platelet aggregation is associated with P2Y12 gene sequence variations in healthy subjects
    Fontana, P
    Dupont, A
    Gandrille, S
    Bachelot-Loza, C
    Reny, JL
    Aiach, M
    Gaussem, P
    CIRCULATION, 2003, 108 (08) : 989 - 995
  • [49] Novel P2Y12 adenosine diphosphate receptor antagonists for inhibition of platelet aggregation (II):: Pharmacodynamic and pharmacokinetic characterization
    Post, Joseph M.
    Alexander, Serene
    Wang, Yi-Xin
    Vincelette, Jon
    Vergona, Ron
    Kent, Lorraine
    Bryant, Judi
    Sullivan, Mark E.
    Dole, William P.
    Morser, John
    Subramanyam, Babu
    THROMBOSIS RESEARCH, 2008, 122 (04) : 533 - 540
  • [50] Adenosine receptor agonists deepen the inhibition of platelet aggregation by P2Y12 antagonists
    Boncler, Magdalena
    Wzorek, Joanna
    Wolska, Nina
    Polak, Dawid
    Watala, Cezary
    Rozalski, Marcin
    VASCULAR PHARMACOLOGY, 2019, 113 : 47 - 56