Belimumab in Lupus Nephritis

被引：1

作者：

Rojas-Rivera, Jorge ^{[1
]}

Ortiz, Alberto ^{[1
]}

Carriazo, Sol ^{[1
]}

机构：

[1] Hosp Univ Fdn Jimenez Diaz, Madrid, Spain

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2021年 / 384卷 / 02期

关键词：

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

To the Editor: Furie et al. (Sept. 17 issue)(1) report the results of the Belimumab International Study in Lupus Nephritis (BLISS-LN), a large, randomized trial of intravenous belimumab as compared with placebo when added to standard therapy (mycophenolate mofetil or cyclophosphamide-azathioprine) in adults with active lupus nephritis. There was adequate follow-up time, but several points need clarification. Notably, one third of the patients were not taking a renin-angiotensin system (RAS) blocker at baseline. Although initiation of an RAS blockade was encouraged, it would have to have been initiated before week 24; treatment would otherwise be considered to have failed. Since . . .

引用

页码：187 / 187

页数：1

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