Application of Palladium-Catalyzed C(sp2)-H Bond Arylation to the Synthesis of Polycyclic (Hetero)Aromatics

被引：116

作者：

Hagui, Wided ^{[1
]}

Doucet, Henri ^{[1
]}

Soule, Jean-Francois ^{[1
]}

机构：

[1] Univ Rennes, CNRS, ISCR UMR 6226, F-35000 Rennes, France

来源：

CHEM | 2019年 / 5卷 / 08期

关键词：

ANNULATIVE PI-EXTENSION; HIGHLY EFFICIENT ROUTE; O-BROMOBENZYL ALCOHOLS; BOWL-SHAPED FRAGMENTS; H DUAL ACTIVATION; ONE-POT SYNTHESIS; AROMATIC-HYDROCARBONS; C-C; STRUCTURAL-ANALYSIS; BENZENESULFONYL CHLORIDES;

D O I：

10.1016/j.chempr.2019.06.005

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Recently, the use of the palladium-catalyzed inter- and/or intra-molecular C-H bond arylations in the building of various pi-extended (hetero)aromatic structures has emerged as a suitable alternative to the previous multi-step synthesis. This new methodology even allowed for the preparation of unprecedented pi-extended molecules owing to perfect control of the reaction sites. This review gives an overview of various syntheses of polycyclic aromatic hydrocarbons (PAHs) and polycyclic heteroaromatics (PCHs) with planar, bowl-shaped, and helical structures prepared in high efficiency and selectivity via Palladium-catalyzed C-H bond arylations.

引用

页码：2006 / 2078

页数：73

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