Beltramo and Piomelli reply — The two most abundant N-acylethanolamines (NAEs) found in chocolate (N-oleyl-ethanolamine and N-linoleylethanolamine) do not activate brain cannabinoid receptors but effectively inhibit anandamide degradation1,2. This observation suggested to us that these compounds might contribute to the hedonic properties of chocolate by causing non-metabolized anandamide to accumulate at its sites of action2.
机构:
Electronic Products, Garden City,, NY, USA, Electronic Products, Garden City, NY, USAElectronic Products, Garden City,, NY, USA, Electronic Products, Garden City, NY, USA
Lieberman, David
Electronic Products (Garden City, New York),
1984,
27
(10):
: 47
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57