Insight into pharmaceutical and personal care products removal using constructed wetlands: A comprehensive review

Pharmaceutical and personal care products (PPCPs) were regarded as emerging environmental pollutants due to their ubiquitous appearance and high environmental risks. The wastewater treatment plants (WWTPs) became the hub of PPCPs receiving major sources of PPCPs used by humans. Increasing concern has been focused on promoting cost-effective ways to eliminate PPCPs within WWTPs for blocking their route into the environment through effluent discharging. Among all advanced technologies, constructed wetlands (CWs) with a combination of plants, substrates, and microbes attracted attention due to their cost-effectiveness and easier maintenance during long-term operation. This study offers baseline data for risk control and future treatment by discussing the extent and dispersion of PPCPs in surface waters over the past ten years and identifying the mechanisms of PPCPs removal in CWs based on the up-to-present research, with a special focus on the contribution of sediments, vegetation, and the interactions of microorganisms. The significant role of wetland plants in the removal of PPCPs was detailed discussed in identifying the contribution of direct uptake, adsorption, phytovolatilization, and biodegradation. Meanwhile, the correlation be-tween the physical-chemical characteristics of PPCPs, the configuration operation of wetlands, as well as the environ-mental conditions with PPCP removal were also further estimated. Finally, the critical issues and knowledge gaps before the real application were addressed followed by promoted future works, which are expected to provide a com-prehensive foundation for study on PPCPs elimination utilizing CWs and drive to achieve large-scale applications to treat PPCPs-contaminated surface waters.