The change in climate elements such as rainfall and temperature are determinant factors of hydrological components (e.g., streamflow, water yield, evapotranspiration). Thus, understanding the trends of hydro-climate variables are imperative for planning water resources management measures. This study examines the trends of precipitation and temperature (1980-2014) as well as streamflow (1990-2008) changes in the Jemma sub-basin of the Upper Blue Nile (Abbay) Basin. A homogeneity test was performed for pre-processing data to inspect the statistical nature of data homogeneity viz., Pettitt's, SNHT, Buishand range test, and Von Neumann test (VNT). The Mann-Kendall (MK) test, Modified Mann-Kendall (MMK) test, Sen's slope estimator, and Innovative trend analysis (ITA) were applied to compute the existence of trend and the magnitude of change at an annual timescale. In a nutshell, the study portrays a change in the trends of hydro-climate variables when using different statistical tests. The result showed that the mean annual temperature in many stations depicted upward trends. There is a significant increasing trend (p < 0.05) by 0.029 degrees C per year in the mean annual temperature of all climatic stations. Based on Sen's slope estimator, the annual precipitation and streamflow were increased by 1.781 mm/year and 0.085 m(3)/s, respectively. But no significant trends were detected in precipitation and streamflow when using Sen's slope estimator test. The results of this study are worthwhile for evaluating the trends of hydro-climatic variables in other areas of Ethiopia in particular and elsewhere in the world in general, which are fundamental for planning water resource management measures.